A method for correlating in vivo prostate magnetic resonance imaging and histopathology using individualized magnetic resonance -based molds

Vijay Shah; Thomas Pohida; Baris TurkbeyHaresh ManiMaria MerinoPeter A. PintoPeter ChoykeMarcelino Bernardo

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A method for correlating in vivo prostate magnetic resonance imaging and histopathology using individualized magnetic resonance -based molds

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摘要

A method for the design and rapid manufacture of a patient specific tissue slicing device based on in vivo images in order to facilitate the process of correlating the images with histopathology is presented. The method is applied to radical prostatectomy specimens where the customized mold is designed using magnetic resonance (MR) images of each patient obtained prior to surgery. In this case, the mold holds the prostate in place while a knife with a single blade or multiple blades is inserted in slots which are positioned to obtain tissue blocks corresponding to the slices in the MR images. The resulting histological specimens demonstrate good anatomical correlation with the MR images.

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来源
《Review of Scientific Instruments》 |2009年第10期|104301-1-104301-6|共6页
作者
Vijay Shah; Thomas Pohida; Baris TurkbeyHaresh ManiMaria MerinoPeter A. PintoPeter ChoykeMarcelino Bernardo;
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作者单位

Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20892, USA;

Molecular Imaging Program, National Cancer Institute, Bethesda, Maryland 20892, USA;

Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland 20892, USAUrologic Oncology Branch, National Cancer Institute, Bethesda, Maryland 20892, USAImaging Physics, SAIC Frederick, Inc., NCI-Frederick, Frederick, Maryland 20892, USA;

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正文语种英语
中图分类仪器、仪表;
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机译：Impedance magnetic resonance imaging: A method for imaging of impedance distributions based on magnetic resonance imaging
2. Findings in 1,123 Men with Preoperative Ga-68-Prostate-Specific Membrane Antigen Positron Emission Tomography/Computerized Tomography and Multiparametric Magnetic Resonance Imaging Compared to Totally Embedded Radical Prostatectomy Histopathology: Implications for the Diagnosis and Management of Prostate Cancer (vol 207, pg 573, 2021) [J] . DAndrea David, Black Peter C., Zargar HomayounDinney Colin P.Soria FrancescoCookson Michael S.Montgomery Jeffrey S.Kassouf WassimDallEra Marc A.Sridhar Srikala S.McGrath John S.Wright Jonathan L.Thorpe Andrew C.Holzbeierlein Jeff M.Carrion Diego M.Di Trapani EttoreBivalacqua Trinity J.North ScottBarocas Daniel A.Lotan YairGrivas PetrosStephenson Andrew J.van Rhijn Bas W.Daneshmand SiamakSpiess Philippe E.Shariat Shahrokh F.Zargar-Shoshtar KamranMertens Laura S.Fairey Adrian S.Mir Maria C.Krabbe Laura-MariaJacobsen Niels-ErikVasdev NikhilYu Evan Y.Xylinas EvanguelosPradere BenjaminPichler RenateCampain Nicholas J.Seah Jo-AnErcole Cesar E.Horenblas SimonAning JonathanMorgan Todd M.Shah Jay B.Moschini Marco The Journal of Urology . 2022,第5期

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A method for correlating in vivo prostate magnetic resonance imaging and histopathology using individualized magnetic resonance -based molds

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