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Tissue engineering: application of pluripotent stem cells in traumatology and orthopedic surgery

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Tissue engineering in orthopedic surgery is becoming increasingly popular, and its clinical application is a fact though the true possibilities of the technique are not known. Matrixes were initially used, followed by growth factors and, more recently, cultured cells or cells obtained from bone marrow aspirates. A review is made of the characteristics of pluripotent mesenchymal cells and their clinical applications.

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