...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Egyptian Journal of Basic and Applied Sciences >Serum substance P level as a marker for subclinical rheumatoid arthritis activity
【24h】

Serum substance P level as a marker for subclinical rheumatoid arthritis activity

机译：

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

ABSTRACT Background Regular assessments of disease activity are essential to prevent the progression of rheumatoid arthritis (RA).Aim of the work This study aimed to assess the utility of serum substance P (SP) level as a marker for RA activity and to establish the value of SP level for the diagnosis of subclinical RA activity.Patients and Methods The study included three groups each 30.subject Group 1 was with minimal or no disease, group 2 had moderate to severe disease activity and group 3 was healthy controls. RA patients were assessed using a Disease Activity Score-28 (DAS28) and power Doppler ultrasonography measurement of the synovitis total score. The serum substance P levels of study groups were assessed using ELISA technique.Results Statistically significant difference in serum SP level was detected in RA patients compared to controls (p ≤ 0.001) and between different disease activity groups (p ≤ 0.001). The best cut off SP value to distinguish patients in subclinical activity active disease patients was 555.5 pg/ml. This had a diagnostic sensitivity, specificity, and accuracy of 96.7, 80 and 88.3 , respectively.Conclusion Serum SP can be used as an indicator of RA disease activity even in those with subclinical activity.

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号