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A quantitative analysis of craniopharyngioma cyst expansion during and after radiation therapy and surgical implications

机译:放射治疗期间和之后颅咽管瘤囊肿扩展的定量分析及其手术意义

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OBJECTIVE When complete resection of craniopharyngioma is not achievable or the sequelae are prohibitive, limited surgery and radiation therapy have demonstrated excellent local disease control while minimizing treatment-related sequelae. When residual tissue exists, there is a propensity for further cyst development and expansion during and after radiation therapy. This can result in obstructive hydrocephalus, visual changes, and/or clinical decline. The authors present a quantitative analysis of cyst expansion during and after radiotherapy and examine how it affected subsequent management.
机译:目的当无法完全切除颅咽管瘤或后遗症不可行时,有限的手术和放射疗法已显示出对局部疾病的良好控制,同时最大程度地减少了与治疗有关的后遗症。当存在残留组织时,在放射治疗期间和之后存在进一步的囊肿发展和扩张的趋势。这可能导致阻塞性脑积水,视力改变和/或临床下降。作者对放疗期间和放疗后的囊肿扩展进行了定量分析,并研究了其如何影响后续治疗。

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