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首页> 外文期刊>Neurosurgical review. >Classification and surgical approaches for transnasal endoscopic skull base chordoma resection: a 6-year experience with 161 cases
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Classification and surgical approaches for transnasal endoscopic skull base chordoma resection: a 6-year experience with 161 cases

机译：经鼻内镜下颅底脊索瘤切除术的分类和手术方法：6年经验161例

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摘要

The aim of this study is to retrospectively analyze 161 cases of surgically treated skull base chordoma, so as to summarize the clinical classification of this tumor and the surgical approaches for its treatment via transnasal endoscopic surgery. Between August 2007 and October 2013, a total of 161 patients (92 males and 69 females) undergoing surgical treatment of skull base chordoma were evaluated with regard to the clinical classification, surgical approach, and surgical efficacy. The tumor was located in the midline region of the skull base in 134 cases, and in the midline and paramedian regions in 27 cases (extensive type). Resection was performed via the transnasal endoscopic approach in 124 cases (77 %), via the open cranial base approach in 11 cases (6.8 %), and via staged resection combined with the transnasal endoscopic approach and open cranial base approach in 26 cases (16.2 %). Total resection was achieved in 38 cases (23.6 %); subtotal resection, 86 cases (53.4 %); partial resection of 80-95 %, 29 cases (18 %); and partial resection < 80 %, 8 cases (5 %). The clinical classification method used in this study seems suitable for selection of transnasal endoscopic surgical approach which may improve the resection degree and surgical efficacy of skull base chordoma. Gross total resection of skull base chordoma via endoscopic endonasal surgery (with addition of an open approach as needed) is a safe and viable alternative to the traditional open approach.
机译：这项研究的目的是回顾性分析161例经手术治疗的颅底脊索瘤病例，以总结该肿瘤的临床分类及其经鼻内镜手术的治疗方法。在2007年8月至2013年10月之间，共对161例接受颅底脊索瘤手术治疗的患者（男性92例，女性69例）进行了临床分类，手术方法和手术效果的评估。肿瘤位于颅底中线区134例，中线和旁中区27例（广泛型）。经鼻内窥镜手术124例（77％），经开颅颅底入路术11例（6.8％），经鼻内镜下开放颅底入路联合分期切除术26例（16.2）。 ％）。 38例（23.6％）实现了全切除。大部切除术86例（53.4％）;部分切除80-95％，29例（18％）;且部分切除<80％，8例（5％）。本研究中使用的临床分类方法似乎适合选择经鼻内窥镜手术方法，这可能会改善颅底脊索瘤的切除程度和手术疗效。通过内窥镜鼻内窥镜手术（根据需要增加开放途径）大体切除颅底脊索瘤是一种安全可行的替代传统开放途径的方法。

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