Chemical journey of somatic cells to pluripotency

Abbey D.

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Chemical journey of somatic cells to pluripotency

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© 2022, The Author(s).Reprogramming somatic cells to pluripotent stem cells has revolutionized the biomedical field by providing enormous hopes and opportunities for the regeneration of tissues and organs for transplantation. Using a small molecule cocktail of epigenetic modifiers and cell signalling inhibitors, a chemical-based easy and controllable technique for converting human somatic cells into chemically induced pluripotent stem cells was recently reported (Guan, Nature 605:325–31, 2022). This novel approach offers well-defined, safe, simple, easy, and clinical-grade manufacturing strategies for modifying the fate of human cells required for regenerative therapeutics.

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《cell regeneration》 |2022年第1期|共页
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Abbey D.;
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Institute for Stem Cell Science and Regenerative Medicine;

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3. Reprogramming somatic cells towards pluripotency by cellular fusion [J] . Soza-Ried Jorge, Fisher Amanda G. Current Opinion in Genetics & Development . 2012,第5期

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Chemical journey of somatic cells to pluripotency

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