Protocols and data analysis in quantitative optothermal in vivo transdermal diffusion measurements

Xiao P.; Cowen JA.; Imhof RE.

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Protocols and data analysis in quantitative optothermal in vivo transdermal diffusion measurements

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We report the development of measurement protocols and data analysis techniques that allow the optothermal diffusion measurements of externally applied substances through human skin to be interpreted quantitatively. We present the theoretical background relating measured optothermal decay times to surface concentration, from which mass diffusion and partition coefficients can be calculated. The methods are illustrated using propylene glycol and a number of other diols as examples. (C) 2003 American Institute of Physics. References: 8

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《Review of Scientific Instruments》 |2003年第1期|767-769|共3页
作者
Xiao P.; Cowen JA.; Imhof RE.;
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正文语种英语
中图分类一般性问题;
关键词
Percutaneous-absorption; Skin;

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Protocols and data analysis in quantitative optothermal in vivo transdermal diffusion measurements

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