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首页> 外文期刊>journal of clinical and diagnostic research >Buccal Mucosa Squamous Cell Carcinoma: Analysis of ECOG Performance Status and its Association with Sociodemographic, Socioeconomic, Clinico-Pathologic Factors and Overall Survival
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Buccal Mucosa Squamous Cell Carcinoma: Analysis of ECOG Performance Status and its Association with Sociodemographic, Socioeconomic, Clinico-Pathologic Factors and Overall Survival

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Despite, progress in cancer therapeutics, survival remains very poor due to various factors. However, treatment decision making is an important factor for a better survival outcome.Aim: To evaluate Eastern Cooperative Oncology Group Performance Status (ECOG-PS) in buccal mucosa squamous cell carcinoma and its association with sociodemographic, socioeconomic, clinicopathologic factors and overall survival.Materials and Methods: This prospective study was conducted in the Regional Cancer Centre, Tamil Nadu between March 2013 and January 2016. Chi-square test and binary logistic regression were performed to evaluate the association between the covariates and ECOG-PS. Further, Kaplan-Meier and log-rank test were used for survival analysis. All statistical significance was set at pResults: A total of 198 subjects which comprised 125 (63.1) male and 73 (36.9) female. In the study, demographic characteristics (Gender, Age, Body mass index and Risk habits) were failed to show the significance whereas socioeconomic status (p=0.001) and clinicopathological features like cell differentiation (p=0.034), TNM stage (p=0.001), lymph node status (p=0.001) and metastasis (p=0.001) exhibited significant association at pConclusion: The present study concludes that the subject’s physical performance score using ECOG-PS scale at diagnosis may help to identify aggressiveness of the disease and may help medical care requirements, specific therapeutic and rehabilitative interventions.

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