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首页> 外文期刊>Caries research >Effect of acidulated phosphate fluoride gel application time on enamel demineralization of deciduous and permanent teeth
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Effect of acidulated phosphate fluoride gel application time on enamel demineralization of deciduous and permanent teeth

机译：酸化氟化磷凝胶施涂时间对乳牙和恒牙珐琅质脱矿质的影响

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Although the effect of acidulated phosphate fluoride gel (APF gel) on caries reduction in permanent teeth is based on evidence, the relevance of the clinical application time is still under debate. Also, the effect of 4- versus 1-min application has not been evaluated in deciduous enamel. In a blind, crossover, in situ study of 14 days, 16 adult volunteers wore palatal appliances containing slabs of human permanent and deciduous enamel. At the beginning of each phase, the slabs were submitted to one of the following treatments: no APF application (negative control); APF gel (1.23% F) application for 1 or 4 min. Biofilm accumulation on the slab surface was allowed and the slabs were subjected eight times a day to 20% sucrose, simulating a high cariogenic challenge condition. On the 15th day of each phase, fluoride retained as CaF 2 and fluorapatite (FAp) was determined on the enamel of the slabs and demineralization was assessed by cross-sectional microhardness. Fluoride as CaF 2 and FAp, formed by APF gel application on the enamel slabs not subjected to the cariogenic challenge, was also determined. APF gel reduced demineralization in both enamel types (p 0.05), but the difference between 1 and 4 min was not statistically significant (p 0.05). CaF 2 and FAp formed and retained on deciduous and permanent enamel was significantly higher in APF gel groups (p 0.05), but no significant difference was found between 1 and 4 min (p 0.05). The findings suggest that 1 min of APF gel application provides a similar effect on inhibition of demineralization as 4 min, for both permanent and deciduous enamel.
机译：尽管酸化磷酸盐氟化物凝胶（APF凝胶）对恒牙减少龋齿的作用是基于证据的，但临床应用时间的相关性仍在争论中。同样，在乳牙釉质中未评估4分钟和1分钟的应用效果。在一项为期14天的盲目，交叉，原位研究中，有16名成年志愿者穿着containing骨器具，其中装有人类永久性和乳腺珐琅质平板。在每个阶段的开始，将板坯进行以下处理之一：不应用APF（阴性对照）;不使用APF。 APF凝胶（1.23％F）应用1或4分钟。允许生物膜积聚在平板表面上，并且每天对平板进行八次20％的蔗糖试验，以模拟高致龋性攻击条件。在每个阶段的第15天，在平板搪瓷上测定保留为CaF 2的氟化物和氟磷灰石（FAp），并通过横截面显微硬度评估其脱矿质。还确定了氟化物CaF 2和FAp，它是通过在未受到致龋性刺激的牙釉质平板上通过APF凝胶施加而形成的。 APF凝胶可减少两种牙釉质的脱矿质（p <0.05），但1和4分钟之间的差异无统计学意义（p> 0.05）。在APF凝胶组中，形成并保留在落叶和永久性牙釉质上的CaF 2和FAp显着更高（p <0.05），但在1-4分钟之间没有发现显着差异（p> 0.05）。研究结果表明，对于永久性和落叶性牙釉质，应用1分钟的APF凝胶对脱矿质的抑制作用与4分钟时相似。

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