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Maternal transfer of hantavirus antibodies in rats

机译:汉坦病毒抗体在大鼠中的母源转移

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Hantaviruses (genus Hantavirus, family Bunyaviridae) causing hemorrhagic fever with renal syndrome (HFRS) are widely distributed throughout the world and are capable of infecting rodents and humans (1). The genus Hantavirus comprises approximately 20 species, including those causing Old World hantavirus infections (i.e., Hantaan, Seoul, Puumala, and Dobrova) and hantavirus pulmonary syndrome (HPS), an acute respiratory distress syndrome first recognized in 1993 as being caused by a New World hantavirus (2). The term HFRS denotes a group of clinically similar diseases that occur throughout Eurasia and adjoining areas. Hantavirus pulmonary syndrome has been reported in North and South America, and the virus involved causes an acute respiratory tract disease (3). Capillary leakage is localized exclusively in the lungs, and death occurs from shock and cardiac complications (4). Rodents serve as the natural reservoirs of these viruses, whereas humans are incidental, end-stage hosts.
机译:导致肾综合征出血热(HFRS)的汉坦病毒(汉坦病毒属,布尼亚病毒科)在世界范围内广泛分布,能够感染啮齿动物和人类(1)。汉坦病毒属包括大约20种,其中包括引起旧世界汉坦病毒感染的物种(即汉坦,汉城,普马拉和多布罗娃)和汉坦病毒性肺综合征(HPS),这是一种急性呼吸窘迫综合征,最早于1993年被确认是由新人类引起的。世界汉坦病毒(2)。术语HFRS表示在整个欧亚大陆及毗邻地区发生的一组临床相似疾病。在北美洲和南美洲已经报道了汉坦病毒性肺综合征,该病毒引起急性呼吸道疾病(3)。毛细血管渗漏仅局限在肺部,死于休克和心脏并发症(4)。啮齿动物是这些病毒的天然宿主,而人类则是偶然的,最终阶段的宿主。

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