One Year in the Life of a Rapid Syndromic Panel for Meningitis/Encephalitis: a Pediatric Tertiary Care Facility's Experience

Naccache Samia N.; Lustestica Maryann; Fahit MargilMestas JavierBard Jennifer Dien

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One Year in the Life of a Rapid Syndromic Panel for Meningitis/Encephalitis: a Pediatric Tertiary Care Facility's Experience

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Early establishment of infectious processes allows for expedited clinical management of meningitis and encephalitis. The FilmArray meningitis/encephalitis (FA-M/E) panel provides rapid detection of potential pathogens associated with encephalitis/ meningitis in both immunocompetent and compromised patients. Here, we conducted a 1-year review of the performance of the FA-M/E panel at a tertiary care children's hospital. Two hundred sixty-five samples from 251 patients were tested. We found 87.25 (219/251) were negative, 9.96 (25/251) were positive for viral analytes, and 3.19 (8/251) were positive for bacterial analytes. When possible, positive results were confirmed by alternate testing; 4/6 available bacterial positives and 17/20 available viral positives were confirmed by retrospective culture or molecular testing.

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来源
《Journal of Clinical Microbiology》 |2018年第5期|e01940-17-e01940-17|共11页
作者
Naccache Samia N.; Lustestica Maryann; Fahit MargilMestas JavierBard Jennifer Dien;
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作者单位

Childrens Hosp Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA 90027 USA;

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原文格式 PDF
正文语种英语
中图分类医学微生物学（病原细菌学、病原微生物学）;
关键词
encephalitis; FilmArray; meningitis; pediatric; syndromic panel;

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One Year in the Life of a Rapid Syndromic Panel for Meningitis/Encephalitis: a Pediatric Tertiary Care Facility's Experience

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