...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Egyptian Journal of Basic and Applied Sciences >Lymphotoxin-α C804A polymorphism and the presence of simple endometrial hyperplasia in Egyptian women
【24h】

Lymphotoxin-α C804A polymorphism and the presence of simple endometrial hyperplasia in Egyptian women

机译：

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

ABSTRACT Endometrial hyperplasia (EH) is found to be a common diagnosis in women presenting with abnormal uterine bleeding, in advanced stages leading to cancer.  To test the association of endometrial hyperplasia with the lymphotoxin-α (LT-α) C804A polymorphism, a case–control study was performed in Egyptian subjects. The cases comprised 100 endometrial hyperplasia patients, and the controls were 120 females served as control. Results showed that C allele versus A allele was compared in Simple Endometrial hyperplasia (SEH) cases compared to controls, there was no significant difference. In pre-menopausal cases, using the CC genotype as the reference genotype, the CA genotype was associated with a significantly elevated OR of 3.36 (95 CI =1.3–8.2, P = 0.007) in SEH cases compared to control. In addition, dominant genotypes (AA plus CA) were significantly increased in SEH cases compared to controls (OR =0.36, 95 CI =0.15–0.84, P =0.01). In conclusion, the common Lymphotoxin- α C804A polymorphism gene is associated with an increased risk of simple endometrial hyperplasia.

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号