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首页> 外文期刊>Journal of Clinical Microbiology >Lack of correlation of gelatinase production and biofilm formation in a large collection of Enterococcus faecalis isolates. purification
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Lack of correlation of gelatinase production and biofilm formation in a large collection of Enterococcus faecalis isolates. purification

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Enterococci, although part of the normal flora of the human gastrointestinal tract, have been recognized as an important cause of nosocomial infection for over two decades (8,11) and are commonly implicated in urinary tract infections, bactere-mia, intra-abdominal and surgical wound infections, catheter-related infections, and endocarditis (11). Enterococci have also been associated with the production of biofilms in root canals (3), on different biomaterials (1, 7, 9, 20), and on various indwelling medical devices, such as ureteral stents (6), intra-vascular catheters (17), and silicone gastrostomy devices (2). The genetic determinants involved in biofilm formation by Enterococcus faecalis have just begun to be understood (4, 5, 7, 9, 13, 19, 20). Several studies have evaluated esp (9, 19, 20), including one recent study which reported that the presence of esp was significantly associated with the ability to form biofilm on abiotic surfaces (20); that study also found that insertional inactivation of esp of two strains, but not of another, markedly impaired biofilm production.

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