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The complement system.

机译:补体系统。

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摘要

The complement system consists of a tightly regulated network of proteins that play an important role in host defense and inflammation. Complement activation results in opsonization of pathogens and their removal by phagocytes, as well as cell lysis. Inappropriate complement activation and complement deficiencies are the underlying cause of the pathophysiology of many diseases such as systemic lupus erythematosus and asthma. This review represents an overview of the complement system in an effort to understand the beneficial as well as harmful roles it plays during inflammatory responses.
机译:补体系统由严格调控的蛋白质网络组成,这些蛋白质在宿主防御和炎症中起重要作用。补体激活导致病原体的调理作用,并被吞噬细胞清除以及细胞裂解。不适当的补体激活和补体缺乏是许多疾病如系统性红斑狼疮和哮喘的病理生理的根本原因。这篇综述代表了补体系统的概述,旨在了解其在炎症反应过程中发挥的有益和有害作用。

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