The rational use of animals in drug development: Contribution of the innovative medicines initiative

GunnM.; VaudanoE.; GoldmanM.

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The rational use of animals in drug development: Contribution of the innovative medicines initiative

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Animal models are still widely used to assess the efficacy or safety of new pharmaceutical products. Since their limitations in predicting actions of drugs in humans are becoming more and more apparent, there is an urgent need to revisit the use of animals in pharmaceutical research. Herein, we review how the Innovative Medicines Initiative (IMI), the largest public-private partnership in the life sciences, is reducing, refining and replacing the use of animals in the context of its global mission, namely, to boost research and the development of new medicines across the European Union.

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《Alternatives to laboratory animals: ATLA》 |2012年第6期|307-312|共6页
作者
GunnM.; VaudanoE.; GoldmanM.;
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Innovative Medicines Initiative, Avenue de la Toison d'Or 56, 1060 Brussels, Belgium;

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原文格式 PDF
正文语种英语
中图分类动物学;
关键词
Animal research; Disease model; Drug development; Drug safety; Personalised medicine; Toxicology;

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The rational use of animals in drug development: Contribution of the innovative medicines initiative

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