The anatomy and cell cycle evolution of DNA damage signaling and repair foci.

Iliakis G

首页> 外文期刊>Cell cycle >The anatomy and cell cycle evolution of DNA damage signaling and repair foci.

【24h】

The anatomy and cell cycle evolution of DNA damage signaling and repair foci.

机译：DNA损伤信号传导和修复灶的解剖结构和细胞周期进化。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The formation of double strand breaks in the DNA (DSBs) of eukaryotic cells, either by physical and chemical agents, or through errors during DNA replication, initiates a highly coordinated network of reactions aiming at the restoration of genomic integrity through repair, or the demise of the cell through apoptosis or senescence. While frequently these reactions are conveniently separated in signaling, for example to checkpoints, and repair by homologous recombination or non-homologous end joining, it is becoming increasingly evident that signaling and repair are inseparable components of what is now referred as DNA damage response (DDR).

机译：真核细胞DNA（DSBs）中双链断裂的形成，无论是通过物理或化学作用，还是通过DNA复制过程中的错误，都会引发高度协调的反应网络，旨在通过修复或消亡来恢复基因组完整性。通过凋亡或衰老的方式尽管这些反应通常在信号传导中方便地分开，例如到达检查站，并通过同源重组或非同源末端连接进行修复，但越来越明显的是，信号传导和修复是现在所谓的DNA损伤反应（DDR）不可分割的组成部分。）。

著录项

来源
《Cell cycle》 |2010年第3期|共2页
作者
Iliakis G;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词

相似文献

外文文献
中文文献
专利

1. The anatomy and cell cycle evolution of DNA damage signaling and repair foci. [J] . Iliakis G Cell cycle . 2010,第3期

机译：DNA损伤信号传导和修复灶的解剖结构和细胞周期进化。
2. Endosulfan induces cell dysfunction through cycle arrest resulting from DNA damage and DNA damage response signaling pathways [J] . Jialiu Wei, Iianshuang Zhang, Lihua Ren, The Science of the Total Environment . 2017,第JULa1期

机译：硫丹通过DNA损伤和DNA损伤反应信号通路引起的循环停滞诱导细胞功能障碍
3. Radiation induced bystander signals are independent of DNA damage and DNA repair capacity of the irradiated cells. [J] . Kashino G, Suzuki K, Matsuda N, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2007,第1a2期

机译：辐射诱导的旁观者信号与被辐射细胞的DNA损伤和DNA修复能力无关。
4. TOWARDS A NEW BIO-QUANTUM MODEL FOR SIGNALING AND REPAIR OF DNA DAMAGE [C] . AYMARA MARTINEZ ARAGON, JOAO DIAS DE TOLEDO ARRUDA-NETO, YADIRA MEDINA GUEVARA International Symposium on Mathematical and Computational Biology . 2013

机译：朝着用于发信号和修复DNA损伤的新生物量子模型
5. The versatile role of homologous recombination in plant cell: Repair of DNA damage, stress-directed genome evolution and foreign DNA integration. [D] . Boyko, Oleksandr. 2008

机译：同源重组在植物细胞中的多种作用：修复DNA损伤，胁迫指导的基因组进化和外源DNA整合。
6. Radiation induced bystander signals are independent of DNA damage and DNA repair capacity of the irradiated cells [O] . Genro Kashino, Keiji Suzuki, Naoki Matsuda, -1

机译：辐射诱导的旁观者信号与被照射细胞的DNA损伤和DNA修复能力无关
7. NF-kB-dependent DNA damage-signaling differentially regulates DNA double-strand break repair mechanisms in immature and mature human hematopoietic cells [O] . Kraft, D., Rall, M., Wiesmüller, L., 2015

机译：NF-kB依赖的DNA损伤信号在未成熟和成熟的人类造血细胞中差异调节DNA双链断裂修复机制。

The anatomy and cell cycle evolution of DNA damage signaling and repair foci.

摘要

著录项

相似文献

相关主题

期刊订阅