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Molecular techniques should now replace cell culture in diagnostic virology laboratories.

机译:分子技术现在应该取代病毒学诊断实验室中的细胞培养。

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Cell cultures have been important historically for the development of virology. However, I will argue that they are no longer essential for a diagnostic laboratory and should be replaced with nucleic acid detection methods. This change of technology should be cost-neutral once the full costs to the laboratory of cell cultures, including staff time, are calculated. Molecular methods are more sensitive than cell cultures and provide answers much more rapidly, especially for negative samples. Since negative results are frequently as important to our clinical colleagues as positive results, we should change now to routine diagnostic services based upon nucleic acid detection. Copyright 2001 John Wiley & Sons, Ltd.
机译:历史上,细胞培养对于病毒学的发展一直很重要。但是,我认为它们不再是诊断实验室必不可少的,应将其替换为核酸检测方法。一旦计算出细胞培养实验室的全部成本(包括员工时间),这种技术变化就应该是成本中立的。分子方法比细胞培养更敏感,并且提供更快的答案,尤其是对于阴性样品。由于阴性结果对临床同事的重要性通常与阳性结果一样重要,因此我们现在应该基于核酸检测转向常规诊断服务。版权所有2001 John Wiley&Sons,Ltd.

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