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Reporting of occupational and environmental research: use and misuse of statistical and epidemiological methods.

机译:职业和环境研究报告:使用和滥用统计和流行病学方法。

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OBJECTIVES: To report some of the most serious omissions and errors which may occur in papers submitted to Occupational and Environmental Medicine, and to give guidelines on the essential components that should be included in papers reporting results from studies of occupational and environmental health. METHODS: Since 1994 Occupational and Environmental Medicine has used a panel of medical statisticians to review submitted papers which have a substantial statistical content. Although some studies may have genuine errors in their design, execution, and analysis, many of the problems identified during the reviewing process are due to inadequate and incomplete reporting of essential aspects of a study. This paper outlines some of the most important errors and omissions that may occur. Observational studies are often the preferred choice of design in occupational and environmental medicine. Some of the issues relating to design, execution, and analysis which should be considered when reporting three of the most common observational study designs, cross sectional, case-control, and cohort are described. An illustration of good reporting practice is given for each. Various mathematical modelling techniques are often used in the analysis of these studies, the reporting of which causes a major problem to some authors. Suggestions for the presentation of results from modelling are made. CONCLUSIONS: There is increasing interest in the development and application of formal "good epidemiology practices". These not only consider issues of data quality, study design, and study conduct, but through their structured approach to the documentation of the study procedures, provide the potential for more rigorous reporting of the results in the scientific literature.
机译:目的:报告在提交给职业与环境医学的论文中可能发生的一些最严重的遗漏和错误,并就报告职业和环境卫生研究结果的论文中应包含的基本成分提供指导。方法:自1994年以来,“职业与环境医学”组织由医学统计学家组成的小组审查提交的论文,这些论文具有实质性的统计内容。尽管某些研究可能在设计,执行和分析方面存在真正的错误,但在审核过程中发现的许多问题是由于研究基本方面的报告不充分和不完整所致。本文概述了可能发生的一些最重要的错误和遗漏。观察性研究通常是职业和环境医学设计的首选选择。描述了与设计,执行和分析有关的一些问题,这些问题在报告三种最常见的观察性研究设计,横截面,病例对照和队列研究时应予以考虑。给出了每种情况下良好报告实践的例证。这些研究的分析中经常使用各种数学建模技术,其报告给某些作者造成了重大问题。提出了有关建模结果表示的建议。结论:人们对正式的“良好流行病学实践”的开发和应用越来越感兴趣。这些不仅考虑数据质量,研究设计和研究行为的问题,而且通过其对研究过程的文献记录的结构化方法,为在科学文献中更严格地报告结果提供了可能。

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