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The burden of occupational cancer

机译：职业癌的负担

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In this issue of the journal (see p 789), Rushton and colleagues1 report the first detailed estimate of the burden of occupational cancer in the UK. Estimates for all but leukaemia are greater than those currently used in the UK. During the last 25 years a variety of methods and assumptions have been employed to estimate the local, national and global burdens of occupational cancer resulting in attributable fractions ranging- from less than 1% to about 40%.In 1981, Doll and Peto3 estimated that about 4% of all cancer deaths and 12.5% of lung cancer deaths (15% in men) in the USA were attributable to occupational exposures. Lung cancer accounted for almost 70% of occupational cancers and at least l%-2% of all cancer deaths were ascribed to asbestos (see Box 1). These estimates have been widely quoted although they were criticised for various methodological reasons, for example for accepting only "definite" occupational carcinogens but "highly speculative" evidence for dietary risk factors.
机译：在本期杂志（请参阅第789页）中，Rushton及其同事1报告了英国职业性癌症负担的第一个详细估计。除白血病外，所有患者的估计数均高于英国目前使用的估计数。在过去的25年中，已经采用了各种方法和假设来估计职业性癌症在当地，国家和全球的负担，导致可归因的比例从不到1％到大约40％。1981年，Doll和Peto3估计：在美国，约4％的癌症死亡和12.5％的肺癌死亡（男性为15％）归因于职业暴露。肺癌几乎占职业性癌症的70％，而在所有癌症死亡中至少有1％-2％归因于石棉（见专栏1）。尽管由于各种方法上的原因而批评了这些估计值，例如，由于仅接受“确定的”职业致癌物，但饮食风险因素的“高度投机性”证据，这些估计却被广泛引用。

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