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Single-camera sequential-scan-based polarization-sensitive SDOCT for retinal imaging

机译:单相机基于顺序扫描的偏振敏感SDOCT用于视网膜成像

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摘要

A single-camera, high-speed, polarization-sensitive, spectral-domain optical-coherence-tomography system was developed to measure the polarization properties of the in vivo human retina. A novel phase-unwrapping method in birefringent media is described to extract the total reflectivity, accumulative retardance, and fast-axis orientation from a specially designed sequence of polarization states incident on the sample. A quarter-wave plate was employed to test the performance of the system. The average error and standard deviation of retardation measurements were 3.2 deg and 2.3 deg, respectively, and of the fast-axis orientation 1.2 deg and 0.7 deg over the range of 0 deg-180 deg. The depolarization properties of the retinal pigment epithelium were clearly observed in both retardance and fast-axis orientation image. A normalized standard deviation of the retardance and of the fast-axis orientation is introduced to segment the polarization-scrambling layer of the retinal pigment epithelium.
机译:开发了一种单相机,高速,偏振敏感的光谱域光学相干断层扫描系统,以测量体内人视网膜的偏振特性。描述了一种在双折射介质中新颖的相位展开方法,该方法可以从入射到样品上的特殊设计的偏振态序列中提取总反射率,累积延迟和快轴方向。使用四分之一波片来测试系统的性能。延迟测量的平均误差和标准偏差分别为3.2度和2.3度,在0度至180度的范围内,快轴方向的平均误差为1.2度和0.7度。视网膜色素上皮的去极化特性在延迟和快速轴取向图像中均清晰可见。引入延迟和快轴取向的标准化标准偏差以分割视网膜色素上皮的偏振加扰层。

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