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首页> 外文期刊>Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery >Management of the NO neck in moderately advanced squamous carcinoma of the larynx
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Management of the NO neck in moderately advanced squamous carcinoma of the larynx

机译：中度晚期喉鳞癌NO颈的处理

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OBJECTIVE: To assess the oncological efficacy of selective neck dissection (SND) in patients with T3-4 NO laryngeal squamous carcinoma.SUBJECTS AND METHODS: A total of 327 patients underwent 654 neck dissections; each side of the neck was individually evaluated.RESULTS: Three percent of patients who had SND developed regional recurrence (RR) in comparison with 11.7 percent of patients who underwent modified radical neck dissection (MRND) (P = 0.005). Only 3 (0.9%) patients developed RR outside the field of SND. The presence of extracapsular extension (P = 0.002) in node-positive (pN+) group and of microvascular invasion (P = 0.007), together with the type of neck dissection (ND) (P = 0.0003) in node-negative (pNO) group had statistical impact on RR. The development of RR significantly affected disease-specific survival (P = 0.0001). Equivalent rates of RR were found in pN+ (2.6%) or pNO (3.2%) patients treated with SND (P = 0.98) as well as in pN+ patients who underwent SND (2.6%) or MRND (4.7%) (P = 0.85).CONCLUSION: This study confirmed the adequacy of SND as a satisfactory staging and therapeutic procedure, and suggests its use in the treatment of limited node-positive (N+) neck.
机译：目的：评估选择性颈淋巴清扫术（SND）在T3-4 NO喉鳞状细胞癌中的疗效。目的和方法：共有327例患者行654例颈淋巴清扫术。结果：SND患者中有3％发生区域性复发（RR），而接受改良根治性颈淋巴清扫术（MRND）的患者为11.7％（P = 0.005）。仅3例（0.9％）患者在SND领域以外发展为RR。淋巴结阳性（pN +）组存在囊外扩张（P = 0.002），微血管浸润（P = 0.007）以及淋巴结阴性（pNO）的颈清扫类型（ND）（P = 0.0003）组对RR有统计学影响。 RR的发展显着影响特定疾病的生存（P = 0.0001）。在接受SND（p = 0.98）的pN +（2.6％）或pNO（3.2％）患者以及接受SND（2.6％）或MRND（4.7％）的pN +患者中，RR的等效发生率（P = 0.85结论：本研究证实了SND作为令人满意的分期和治疗方法是适当的，并建议将其用于有限的淋巴结阳性（N +）颈部的治疗。

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