• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Seminars in Respiratory and Critical Care Medicine >Sedation and analgesia in mechanical ventilation
【24h】

Sedation and analgesia in mechanical ventilation

机译：机械通气中的镇静镇痛

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Traditionally, critically ill patients undergoing mechanical ventilation (MV) have received sedation. Over the last decade, randomized controlled trials have questioned continued use of deep sedation. Evidence shows that a nurse-driven sedation protocol reduces length of MV compared with standard strategy with sedation. Furthermore, daily interruption of sedation reduces length of MV, intensive care unit (ICU), and hospital length of stay (LOS). A larger scale trial with daily interruption of sedation has confirmed these findings and furthermore showed a reduction in 1-year mortality with the use of daily interruption of sedation. Recently, a strategy with no sedation has been described reporting a reduction in length of MV, ICU, and hospital LOS compared with a strategy with daily interruption of sedation. Follow-up trials report that reducing sedation does not seem to increase the risk of psychological morbidity. Moreover, delirium has gained increased focus in recent years with development of validated tools to detect both hyperactive and hypoactive forms of delirium. Using validated tools for detecting delirium is important in monitoring and detecting acute brain dysfunction in critically ill patients. Evidence from randomized trials also cites a beneficial effect of early mobilization with respect to length of MV and delirium.
机译：传统上，接受机械通气（MV）的重症患者已接受镇静。在过去的十年中，随机对照试验对继续使用深度镇静剂提出了质疑。有证据表明，与采用镇静的标准策略相比，护士驱动的镇静方案可减少MV的长度。此外，每天中断镇静剂可减少MV长度，重症监护病房（ICU）和住院时间（LOS）。一项每天进行镇静的大规模试验已经证实了这些发现，并且进一步表明，每天进行镇静可以降低1年死亡率。最近，已经描述了一种无镇静策略，与每日镇静策略相比，该方法可减少MV，ICU和医院LOS的时间。后续试验报告说，减少镇静作用似乎并不会增加心理疾病的风险。此外，近年来，with妄已通过开发经验证的工具来检测hyper妄和hyperactive形式的ir妄得到越来越多的关注。使用经过验证的工具检测tools妄对于监测和检测重症患者的急性脑功能异常非常重要。随机试验的证据还提到了早期动员对于MV和del妄长度的有益作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号