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首页> 外文期刊>Biomaterials >An overview of the development of artificial corneas with porous skirts and the use of PHEMA for such an application.
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An overview of the development of artificial corneas with porous skirts and the use of PHEMA for such an application.

机译:带有多孔裙边的人造角膜的发展概况以及PHEMA在此类应用中的用途概述。

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摘要

An overview of the efforts to develop functional polymeric artificial corneas (keratoprostheses) by incorporating a porous skirt is presented. The development of such a device by the author's group using poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogels, as a combination of their homogeneous and heterogeneous states, and the rationale of this choice are also discussed. The latest results of the clinical trials with the PHEMA keratoprosthesis in human patients indicate a lower risk of the complications traditionally associated with the implantation of artificial corneas.
机译:概述了通过结合多孔裙来开发功能性聚合物人工角膜(角膜假体)的工作。作者小组使用聚(甲基丙烯酸2-羟乙酯)(PHEMA)水凝胶作为其均相和非均相状态的组合来开发这种装置,并讨论了这种选择的原理。 PHEMA角膜假体在人类患者中进行的临床试验的最新结果表明,传统上与​​人工角膜植入相关的并发症风险较低。

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