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首页> 外文期刊>Spine >Prospective ten-year follow-up study comparing patients with whiplash-associated disorders and asymptomatic subjects using magnetic resonance imaging.
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Prospective ten-year follow-up study comparing patients with whiplash-associated disorders and asymptomatic subjects using magnetic resonance imaging.

机译：一项为期十年的前瞻性随访研究，使用磁共振成像比较了与鞭打相关疾病和无症状受试者的情况。

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STUDY DESIGN: A prospective 10-year follow-up study of patients with whiplash-associated disorders (WAD) and asymptomatic volunteers. OBJECTIVE: To clarify long-term impact of whiplash injury on patient's symptoms and on magnetic resonance imaging (MRI) findings of the cervical spine. SUMMARY OF BACKGROUND DATA: Long-term prognosis of WAD has not been fully elucidated. METHODS: Between 1993 and 1996, we conducted cross-sectional comparative study of 508 acute WAD patients and 497 asymptomatic volunteers, all of whom underwent MRI of the cervical spine. For this follow-up study, 133 WAD patients and 223 control subjects were recruited again. All participants underwent follow-up MRI and physical examination, and answered to questionnaires regarding neck symptoms. Evaluation of MRI included decrease in signal intensity of discs, posterior disc protrusion, disc space narrowing, and foraminal stenosis using 2 to 4 numerical grades. Increase in the numerical grades by one or more was considered to be progression of degenerative changes. RESULTS: Progression of decrease in signal intensity was observed in 109 WAD patients (82.0%), and 132 control subjects (59.2%), (age, sex adjusted odds ratio [OR]: 3.06), posterior disc protrusion in 101 (75.9%) and in 155 (69.5%) (OR = 1.46), disc space narrowing in 33 (24.8%) and in 59 (26.5%) (OR = 0.98), and foraminal stenosis in 6 (4.5%), and in 20 (9.0%) (OR = 0.52), respectively. Neck pain was observed in 34 WAD patients (25.6%) and 22 control subjects (9.9%) (P < 0.0001). There was no statistically significant correlation between neck pain and progression in each MR finding in either group. CONCLUSION: The results of this study suggest that, although some WAD patients are more likely to suffer from long-lasting neck pain, MRI findings cannot explain the symptoms.
机译：研究设计：一项为期10年的前瞻性随访研究，研究对象为有鞭打相关疾病（WAD）和无症状志愿者。目的：阐明鞭打损伤对患者症状和颈椎磁共振成像（MRI）发现的长期影响。背景资料概述：WAD的长期预后尚未完全阐明。方法：从1993年到1996年，我们对508例急性WAD患者和497例无症状志愿者进行了横断面比较研究，他们均接受了颈椎MRI检查。对于该随访研究，再次招募了133名WAD患者和223名对照受试者。所有参与者均接受了MRI和体格检查，并回答了有关颈部症状的问卷。 MRI的评估包括使用2到4个数字等级降低椎间盘信号强度，椎间盘后突出，椎间盘狭窄和椎间孔狭窄。数字等级增加一个或多个被认为是退化性变化的进展。结果：在109名WAD患者（82.0％）和132名对照受试者（59.2％）中观察到信号强度下降的进展，（年龄，性别调整后的优势比[OR]：3.06），在101名椎间盘后突出物（75.9％） ）和155（69.5％）（OR = 1.46）中，椎间盘间隙变窄的分别为33（24.8％）和59（26.5％）（OR = 0.98），以及椎间孔狭窄分别为6（4.5％）和20（分别为9.0％（OR = 0.52）。在34名WAD患者（25.6％）和22名对照受试者（9.9％）中观察到颈部疼痛（P <0.0001）。两组中每个MR发现的颈部疼痛与进展之间无统计学意义的相关性。结论：这项研究的结果表明，尽管一些WAD患者更有可能遭受长期的颈部疼痛，但MRI结果不能解释这些症状。

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