Novel challenges of multi-society investigator-initiated studies: A paradigm shift for technique and technology evaluation

SchwaitzbergS.D.; HawesR.H.; RattnerD.W.; KochmanM.L.

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Novel challenges of multi-society investigator-initiated studies: A paradigm shift for technique and technology evaluation

机译：多社会研究者发起的研究的新挑战：技术和技术评估的范式转变

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The introduction of innovative techniques and novel technologies into clinical practice is a challenge that confronts all aspects of healthcare delivery. Upheaval from shrinking research funding and declining healthcare reimbursements now forces patients, doctors, hospitals, payers, regulators, and even health systems into conflict as new therapies struggle to find a place in the therapeutic armamentarium. The escalating costs of healthcare force all parties to consider both the medical risks/benefits as well as the economic efficiency of proposed tools and therapies. We highlight these challenges by examining the process of initiating and conducting a "society-as- investigator" clinical trial to assess the safety of the natural orifice translumenal endoscopic surgery (NOTES) approach to cholecystectomy in the context of the issues that confront technology diffusion today.

机译：将创新技术和新颖技术引入临床实践是医疗保健提供方方面面的挑战。由于新疗法难以在治疗性武器库中找到一席之地，研究经费减少和医疗保健报销下降引起的动荡现在迫使患者，医生，医院，付款人，监管者甚至卫生系统发生冲突。医疗保健费用的不断上涨迫使各方都考虑医疗风险/益处以及拟议工具和疗法的经济效率。我们通过检查启动和进行“社会研究者”临床试验的过程来突显这些挑战，以评估当今技术扩散所面临的问题中自然孔腔内镜手术（NOTES）方法进行胆囊切除术的安全性。

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《Surgical Endoscopy》 |2013年第8期|共5页
作者
SchwaitzbergS.D.; HawesR.H.; RattnerD.W.; KochmanM.L.;
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正文语种 eng
中图分类诊断学;
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Comparative effectiveness; Conflict of interest; cholecystectomy; Natural orifice; NOTES;

机译：比较效果;利益冲突;胆囊切除术;自然孔口;NOTES;

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8. Study and Evaluation of Modular Packaging Techniques for on Board Data Handling: Technology Assessment [R] . Perry, J. 1979

机译：板载数据处理模块化封装技术的研究与评估：技术评估

Novel challenges of multi-society investigator-initiated studies: A paradigm shift for technique and technology evaluation

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