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Medical Research and Evaluation Facility (MREF) and Studies Supporting theMedical Chemical Defense Program. Determination of the Minimum Effective Pyridostigmine Pretreatment Dose in Monkeys Challenged with 5 X LD50 Soman and Treated with Atropine/2-Pam

机译：医学研究和评估机构（mREF）和支持医学化学防御计划的研究。用5×LD50索曼攻击猴子并用阿托品/ 2-pam处理的最小有效吡啶斯的明预处理剂量的测定

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This task was conducted to determine the minimum dose of pyridostigmine (PYR),and the associated level of erythrocyte acetycholinesterase inhibition (AChE-I), that provides protection from 5 X 48-br GD LD50 of untreated monkeys. Monkeys were injected im with GD and treated with 0.4 mg atropine (ATR) free base and 25.7 mg pralidoxime (2-PAM) per kg BW.

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作者
Olson, C. T.; Menton, R. G.; Kiser, R. C.; Hayes, T. L.; Matthews, M. C.;
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年度 1995
页码
总页数 180
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Defense systems; Chemical warfare; Medical research; Acetylcholinesterase; Cholinesterase inhibitors; Pyridostigmine bromide; Pyridines; Peak values; Dosage; Erythrocytes; Preventive medicine; Atropine; Monkeys;

机译：防御系统;化学战;医学研究;乙酰胆碱酯酶;胆碱酯酶抑制剂;吡啶斯的明;吡啶类;峰值;剂量;红细胞;预防医学;阿托品;猴子;

Medical Research and Evaluation Facility (MREF) and Studies Supporting theMedical Chemical Defense Program. Determination of the Minimum Effective Pyridostigmine Pretreatment Dose in Monkeys Challenged with 5 X LD50 Soman and Treated with Atropine/2-Pam

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