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首页> 美国政府科技报告 >Report of the Prevention of Perinatal HIV Type 1 Transmission Workshop:Conference Summary. Conference on Advances in AIDS Vaccine Development-1994
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Report of the Prevention of Perinatal HIV Type 1 Transmission Workshop:Conference Summary. Conference on Advances in AIDS Vaccine Development-1994

机译：预防围产期HIV 1型传播研讨会报告：会议纪要。艾滋病疫苗发展进展会议 - 1994年

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In February 1994, interim analysis of ACTG 076 disclosed a 67% reduction intransmission from mother to infant through aggressive intervention with AZT (1) Subsequently, the use of AZT in pregnancies complicated by MTV infection has been recommended by the U.S. Public Health Service (2) In addition, recommendations regarding HIV testing in pregnancy have been reassessed to maximize the benefit from this new therapeutic paradigm (3) This critical study has also transformed the landscape of research into the pathophysiology and interdiction of perinatal HIV infection worldwide. It is now evident that successful interdiction of HIV transmission is feasible and that maternal-infant transmission is a practical and efficient study setting for transmission research. In order to review the global research effort to prevent perinatal HIV transmission in the wake of 076, a workshop was organized at the Seventh Annual Meeting of the National Cooperative Vaccine Development Groups for AIDS in Reston, Virginia on November 6, 1994 entitled Workshop on Perinatal Intervention of HIV-1 transmission. The specific goals of the workshop were to survey ongoing and planned intervention research on a global scale, identify potential study sites which were not already engaged in clinical trials and review potential agents/strategies which might be evaluated.

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