Triplex Forming Therapeutic Agents for Breast Cancer

机译：三联形成乳腺癌治疗药物

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The overall goal of this proposal was to develop sequence specific DNA bindingcompounds which are targeted to the promoters of the c-myc, c-Ha-ras, and neu genes. Inhibition of expression of these genes, which appear to play an important role in the development of the malignant phenotype of breast carcinoma cells would be expected to inhibit cellular proliferation and possibly induce apoptosis.

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作者
Miller, D. M.;
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年度 1995
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总页数 71
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Deoxyribonucleic acids; Genes; Breast cancer; Epithelium; Neoplasms; Therapy; Carcinogens; Inhibition; Cells(Biology); Mammary glands; Nucleotides;

机译：脱氧核糖核酸;基因;乳腺癌;上皮;肿瘤;治疗;致癌物;抑制;细胞（生物学）;乳腺;核苷酸;

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专利

1. American ginseng and breast cancer therapeutic agents synergistically inhibit MCF-7 breast cancer cell growth. [J] . Duda RB, Zhong Y, Navas V, Journal of Surgical Oncology . 1999,第4期

机译：西洋参和乳腺癌治疗剂可协同抑制MCF-7乳腺癌细胞的生长。
2. American ginseng and breast cancer therapeutic agents synergistically inhibit MCF-7 breast cancer cell growth. [J] . Duda RB, Zhong Y, Navas V, Journal of Surgical Oncology . 1999,第4期

机译：西洋参和乳腺癌治疗剂可协同抑制MCF-7乳腺癌细胞的生长。
3. Anticancer effects of metformin and its potential use as a therapeutic agent for breast cancer. [J] . Guppy A, Jamal Hanjani M, Pickering L Future oncology . 2011,第6期

机译：二甲双胍的抗癌作用及其作为乳腺癌治疗剂的潜在用途。
4. Breast Cancer-specific Delivery of Therapeutic microRNA with Novel Breast Cancer-targeting Cell Penetrating Peptide-conjugated Gene Carrier [C] . Hwa Jeong Lee, Ran Namgung, Won Jong Kim, World biomaterials congress . 2012

机译：新型靶向乳腺癌的细胞穿透肽偶联基因载体与治疗性microRNA的乳腺癌特异性递送。
5. Effects of adenine nucleotide agents and their therapeutic potential on triple negative breast cancer. [D] . Lertsuwan, Jomnarong. 2014

机译：腺嘌呤核苷酸试剂及其对三阴性乳腺癌的治疗潜力。
6. Suppression of c-myc oncogene expression by a polyamine-complexed triplex forming oligonucleotide in MCF-7 breast cancer cells. [O] . T J Thomas, C A Faaland, M A Gallo, 1995

机译：多胺复合三链体形成寡核苷酸在MCF-7乳腺癌细胞中抑制c-myc癌基因表达。
7. Identification of Significant Genes and Therapeutic Agents for Breast Cancer by Integrated Bioinformatics [O] . Xiao Sun, Zhenzhen Luo, Liuyun Gong, 2021

机译：综合生物信息学鉴定乳腺癌的显着基因和治疗剂
8. Triplex Forming Therapeutic Agents for Breast Cancer [R] . Miller, D. M. 1995

机译：三联形成乳腺癌治疗药物

Triplex Forming Therapeutic Agents for Breast Cancer

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