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Determination of Fifty Percent Inhibitory Concentrations of Antimalaria DrugsAgainst Plasmodium Falciparum Parasites in a Serum-Free Medium

机译：在无血清培养基中测定50％抑制浓度的抗疟药物对恶性疟原虫寄生虫的影响

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The obligate requirement for serum in this assay presents difficulties in thedirect comparison of IC-50 results among laboratories. We now have evidence that antimalarial drug sensitivity assays can be reliably performed in a serum-free medium.

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Ofulla, A. O.; Orago, A. S.; Githure, J. I.; Burans, J. P.; Aleman, G. M.;
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年度 1994
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总页数 6
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Parasites; Drugs; Plasmodium falciparum; Antimalarials; Comparison; Sensitivity; Microscopy; Inhibition; Assaying; Cultures(Biology); Reprints;

机译：寄生虫;药物;恶性疟原虫;抗疟药;比较;敏感性;显微镜检查;抑制;分析;培养（生物学）;重印;

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1. The presence of leukocytes in ex vivo assays significantly increases the 50-percent inhibitory concentrations of artesunate and chloroquine against Plasmodium vivax and Plasmodium falciparum. [J] . Kaewpongsri S, Sriprawat K, Suwanarusk R, Antimicrobial agents and chemotherapy. . 2011,第3期

机译：在体外分析中白细胞的存在显着提高了青蒿琥酯和氯喹对间日疟原虫和恶性疟原虫的抑制浓度为50％。
2. Estimation of serum-free 50-percent inhibitory concentrations for human immunodeficiency virus protease inhibitors lopinavir and ritonavir. [J] . Hickman D, Vasavanonda S, Nequist G, Antimicrobial agents and chemotherapy. . 2004,第8期

机译：估计人类免疫缺陷病毒蛋白酶抑制剂洛匹那韦和利托那韦的无血清50％抑制浓度。
3. Plasmodium falciparum: differing effects of non-esterified fatty acids and phospholipids on intraerythrocytic growth in serum-free medium. [J] . Asahi H, Izumiyama S, Tolba ME, Experimental parasitology . 2011,第3期

机译：恶性疟原虫：在无血清培养基中非酯化脂肪酸和磷脂对红细胞内生长的不同影响。
4. Parasite Mitochondria as a Target of Chemotherapy Inhibitory Effect of Licochalcone A on the Plasmodium falciparum Respiratory Chain [C] . FUMIKA MI-ICHI, HIROKO MIYADERA, TAMAKI KOBAYASHI, International Conference on Natural Products and Molecular Medicine . 2005

机译：寄生虫线粒体作为Licochalcone A对疟原虫呼吸链的化疗抑制作用的目标
5. The characterization of Plasmodium falciparum iron regulatory-like protein (PfIRPa) in asexual stage Plasmodium falciparum parasites. [D] . Hodges, Marcus G. 2005

机译：无性疟原虫恶性疟原虫中恶性疟原虫铁调节样蛋白（PfIRPa）的表征。
6. Assessment of the Drug Susceptibility of Plasmodium falciparum Clinical Isolates from Africa by Using a Plasmodium Lactate Dehydrogenase Immunodetection Assay and an Inhibitory Maximum Effect Model for Precise Measurement of the 50-Percent Inhibitory Concentration [O] . Halima Kaddouri, Serge Nakache, Sandrine Houzé, 2006

机译：通过使用血浆乳酸乳酸脱氢酶免疫检测法和抑制最大作用模型精确测量50％抑制浓度的非洲恶性疟原虫临床分离株的药物敏感性评估
7. Assessment of the Drug Susceptibility of Plasmodium falciparum Clinical Isolates from Africa by Using a Plasmodium Lactate Dehydrogenase Immunodetection Assay and an Inhibitory Maximum Effect Model for Precise Measurement of the 50-Percent Inhibitory Concentration [O] . Kaddouri, Halima, Nakache, Serge, Houzé, Sandrine, 2006

机译：通过使用血浆乳酸乳酸脱氢酶免疫检测法和抑制最大作用模型精确测量50％抑制浓度的非洲恶性疟原虫临床分离株的药物敏感性评估
8. Determination of Fifty Percent Inhibitory Concentrations (IC50) of AntimalarialDrugs Against Plasmodium Falciparum Parasites in a Serum-Free Medium [R] . Ofulla, A. O., Orago, A. S., Githure, J. I., 1994

机译：无血清培养基中抗疟原虫寄生虫抗疟药物50％抑制浓度（IC50）的测定

Determination of Fifty Percent Inhibitory Concentrations of Antimalaria DrugsAgainst Plasmodium Falciparum Parasites in a Serum-Free Medium

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