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Development of a Rapid Chair-Side Test to Detect Pathogenic Bacteria Associatedwith Periodontal Disease

机译：开发快速椅侧检测法检测与牙周病相关的致病菌

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The purpose of this contract research was to produce a simple and rapid test thatwould identify dental plaque bacteria associated with early detection of periodontal disease. Spirochetes were studied because of their strong correlation with destructive, progressive periodontal disease. Monoclonal antibodies against Treponema pallidum led to the discovery of a previously unrecognized oral spirochetes in plaque at diseased sites and within gingiva near periodontal lesions. in vitro experiments demonstrated that these pathogen-related oral spirochetes (PROS) were capable of moving through living tissue; no other plaque bacteria and no cultivable oral spirochete were invasive. PROS has been found at sites of periodontal disease in HIV-negative people and in people with HIV-associated periodontal disease. Extensive efforts were made to isolate and cultivate PROS so that PROS-specific monoclonal antibodies and DNA probes could be developed for the chair-side test.

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作者
Riviere, G. R.;
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年度 1994
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总页数 3
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Bacteria; Correlation; Dental plaque; Detection; Human immunodeficiency viruses; Lesions; Monoclonal antibodies; Probes; Sites; Spirochaeta; Test and evaluation; Treponema pallidum; Diagnosis(Medicine); In vitro analysis; Gram negative bacteria; Deoxyribo;

机译：细菌;相关性;牙菌斑;检测;人类免疫缺陷病毒;病变;单克隆抗体;探针;位点;螺旋体;试验和评价;梅毒螺旋体;诊断（医学）;体外分析;革兰氏阴性菌;脱氧核糖核酸;

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1. The Ability of Quantitative, Specific, and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases [J] . Saeed Alassiri, Pirjo Parnanen, Nilminie Rathnayake, Disease markers . 2018,第5a6期

机译：对aMMP-8进行定量，特异和敏感的即时护理点/主席侧口服液体免疫测试的能力，可检测牙周和种植周疾病
2. The Ability of Quantitative, Specific, and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases [J] . Alassiri Saeed, Parnanen Pirjo, Rathnayake Nilminie, Disease markers . 2018,第Pta2期

机译：用于AMMP-8的定量，特异性和敏感点的护理/椅子侧口腔液免疫液免疫液体
3. Development of a Rapid Recombinase-Aided Amplification Assay for Testing Disinfection Efficacy of Pathogenic Bacteria in Blood Establishment [J] . Zhu Liwei, Wang Yongjun, Zheng Xiaofan, Transfusion: The Journal of the American Association of Blood Banks . 2018,第S1期

机译：一种快速重组酶辅助扩增测定试验，用于测试血液建立中病原菌的消毒效能
4. Isolation, Amplification and Characterization of Foodborne Pathogen Disease Bacteria Gene for Rapid Kit Test Development [C] . M. Nurjayadi, I. Santoso, I. R. Kartika, International Symposium on Current Progress in Mathematics and Sciences . 2017

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5. An evanescent wave fiber optic biosensor for the rapid detection of pathogenic bacteria using Escherichia coli O157:H7 as a model organism for assay development. [D] . DeMarco, Daniel Robert. 2001

机译：e逝波光纤生物传感器，用于快速检测病原菌，使用大肠杆菌O157：H7作为模型生物进行分析开发。
6. The Ability of Quantitative Specific and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases [O] . Saeed Alassiri, Pirjo Parnanen, Nilminie Rathnayake, 2018

机译：对aMMP-8进行定量特异和敏感的即时护理点/主席侧口服液免疫测试的能力以检测牙周和种植周疾病
7. The Ability of Quantitative, Specific, and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases [O] . Saeed Alassiri, Pirjo Parnanen, Nilminie Rathnayake, 2018

机译：用于AMMP-8的定量，特异性和敏感的护理/椅子侧口腔液体免疫液免疫的能力，以检测牙周和围植入疾病

Development of a Rapid Chair-Side Test to Detect Pathogenic Bacteria Associatedwith Periodontal Disease

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