首页> 美国政府科技报告 >Comparative In vitro Analysis of Proliferation, Ig Secretion, and Ig ClassSwitching by Murine Marginal Zone and Follicular B Cells. (Reannouncement with New Availability Information)

【24h】

Comparative In vitro Analysis of Proliferation, Ig Secretion, and Ig ClassSwitching by Murine Marginal Zone and Follicular B Cells. (Reannouncement with New Availability Information)

机译：小鼠边缘区和滤泡B细胞增殖，Ig分泌和Ig分类的比较体外分析。（重新公布新的可用性信息）

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

We have previously demonstrated that activation of murine B cells by dextran-conjugated anti-IgD antibodies may serve as a polyclonal, in vitro model system for studying immune responses to T cell-independent type 2 (Tl-2) Ag, as exemplified by the bacterial polysaccharides. Because in vivo Ig responses to Tl-2 Ag are mediated primarily by B cells resident in the splenic marginal zone, we wished to determine whether this reflected an intrinsic difference in the responsiveness of marginal zone B cells (MZB) compared with follicular B cells (FB) to this class of Ag. In this report we demonstrate that highly purified MZB, isolated by electronic cell sorting, exhibit a lower proliferative response in

著录项

作者
Snapper, C. M.; Yamada, H.; Smoot, D.; Sneed, R.; Lees, A.;
展开▼
作者单位

展开▼
年度 1993
页码
总页数 10
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Biochemistry; Spleen; Polysaccharides; Salmonella typhimurium; Microbiology; Lymphocytes; Medical research; Reprints;

机译：生物化学;脾脏;多糖;鼠伤寒沙门氏菌;微生物学;淋巴细胞;医学研究;重印;

相似文献

外文文献
中文文献

1. Multivalent cross-linking of membrane Ig sensitizes murine B cells to a broader spectrum of CpG-containing oligodeoxynucleotide motifs, including their methylated counterparts, for stimulation of proliferation and Ig secretion. [J] . Goeckeritz BE, Flora M, Witherspoon K, International immunology. . 1999,第10期

机译：膜Ig的多价交联可使鼠B细胞对更广范围的含CpG的寡脱氧核苷酸基序（包括其甲基化对应物）敏感，以刺激增殖和Ig分泌。
2. IL-3 and granulocyte-macrophage colony-stimulating factor strongly induce Ig secretion by sort-purified murine B cell activated through the membrane Ig, but not the CD40, signaling pathway. [J] . Snapper CM, Moorman MA, Rosas FR, The Journal of Immunology: Official Journal of the American Association of Immunologists . 1995,第11期

机译：IL-3和粒细胞巨噬细胞集落刺激因子通过经分类的纯化的鼠B细胞激活了Ig分泌，该鼠B细胞通过膜Ig激活，但不通过CD40信号通路激活。
3. VprBP Is Required for Efficient Editing and Selection of Ig kappa(+) B Cells, but Is Dispensable for Ig lambda(+) and Marginal Zone B Cell Maturation and Selection [J] . Palmer Victoria L., Aziz-Seible Razia, Kassmeier Michele D., The Journal of Immunology: Official Journal of the American Association of Immunologists . 2015,第4期

机译：VprBP是Ig kappa（+）B细胞的有效编辑和选择所必需的，但是对于Ig lambda（+）和边缘区B细胞的成熟和选择是必不可少的
4. Plasmacytic differentiation of marginal zone and follicular B cells. [D] . Gunn Dye, Kathryn Elaine. 2006

机译：边缘区和滤泡B细胞的浆细胞分化。
5. VprBP is required for efficient editing and selection of Igκ+ B cells but is dispensable for Igλ+ and marginal zone B cell maturation and selection [O] . Victoria L. Palmer, Razia Aziz-Seible, Michele D. Kassmeier, -1

机译：VprBP是有效编辑和选择Igκ+ B细胞所必需的但对于Igλ+和边缘区B细胞成熟和选择是必不可少的
6. VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection [O] . Victoria L. Palmer, Razia Aziz-Seible, Michele D. Kassmeier, 2015

机译：VPRBP需要有效编辑和选择IGκ+ B细胞，但可分配IGλ+和边缘区B细胞成熟和选择

Comparative In vitro Analysis of Proliferation, Ig Secretion, and Ig ClassSwitching by Murine Marginal Zone and Follicular B Cells. (Reannouncement with New Availability Information)

摘要

著录项

相似文献

相关主题

期刊订阅