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Octreotide Changes Serum Thyrotropin (TSH) Glycoisomer Distribution as Assessedby Lectin Chromatography in a TSH Macroadenoma Patient

机译：奥曲肽改变TsH巨腺瘤患者中凝集素色谱法评估的血清促甲状腺激素（TsH）糖异构体分布

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A 28-yr-old woman with hyperthyroidism due to a TSH/GH-secreting macroadenoma wastreated preoperatively with octreotide to attain euthyroidal status. Lectin chromatography, performed on her immunopurified serum TSH obtained at baseline and 1 week after 50 ug three times daily octreotide therapy, revealed a significant increase in ricin binding after octreotide. This result is consistent with increased amounts of TSH isoforms with more exposed galactose residues. Further clinical studies to elucidate the effects of pharmacological agents on serum TSH isoforms and TSH bioactivity are needed. ....TSH, Lectins, Glycosylation, Pituitary.

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作者
Francis, T. B.; Smallridge, R. C.; Kane, J.; Magner, J. A.;
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年度 1993
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总页数 7
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Thyrotropin; Chromatography; Diseases; Galactose; Residues; Ricin; Therapy; Thyroidgland; Diagnosis(Medicine); Pharmacological antagonists; Patients; Genes; Immune serums; Blood serum; Reprints; Pituitary gland; Secretion;

机译：促甲状腺激素;色谱法;疾病;半乳糖;残留物;蓖麻毒素;治疗;甲状腺;诊断（医学）;药理学拮抗剂;患者;基因;免疫血清;血清;重印;脑下垂体;分泌物;

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专利

1. Ability of two new thyrotropin (TSH) assays to separate hyperthyroid patients from euthyroid patients with low TSH. [J] . E Taimela, J Forsstr?m, K Irjala, Clinical Chemistry: Journal of the American Association for Clinical Chemists . 1994,第1期

机译：两种新的促甲状腺激素（TSH）检测方法能够将甲状腺功能亢进症患者与低促甲状腺激素的正常甲状腺患者区分开。
2. TSH-secreting pituitary macroadenoma: rapid tumor shrinkage and recovery from hyperthyroidism with octreotide. [J] . Fischler MP, Reinhart WH Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology . 1999,第1期

机译：TSH分泌型垂体巨腺瘤：肿瘤迅速缩小，使用奥曲肽可从甲状腺功能亢进中恢复。
3. Thyroid Color Flow Doppler Sonography: An Adjunctive Tool for Differentiating Patients with Inappropriate Thyrotropin (TSH) Secretion Due to TSH-Secreting Pituitary Adenoma or Resistance to Thyroid Hormone. [J] . Bogazzi F, Manetti L, Tomisti L, Thyroid: official journal of the American Thyroid Association . 2006,第10期

机译：甲状腺彩色多普勒超声检查：鉴别由于TSH分泌性垂体腺瘤或甲状腺激素抵抗性甲状腺激素（TSH）分泌不适当的患者的辅助工具。
4. Comparative aspects of pituitary glycoproteins, including thyrotropin (TSH) [C] . Duncan C. Ferguson Annual Veterinary Medical Forum . 2000

机译：垂体糖蛋白的比较方面，包括甲状腺激素（TSH）
5. CHROMOSOMAL ASSIGNMENT OF HUMAN GENES FOR GASTRIN, THYROTROPIN (TSH)-β SUBUNIT AND C-erbB-2 BY CHROMOSOME SORTING COMBINED WITH VELOCITY SEDIMENTATION AND SOUTHERN HYBRIDIZATION [D] . Fukushige, Shinichi 1988

机译：染色体分选结合速度沉淀和南部杂交技术对人胃泌素，甲状腺素（TSH）-β亚基和C-erbB-2基因的染色体分配
6. SAT-253 Long-Term Management and Successful Pregnancy of a Patient with a TSH Secreting Macroadenoma Treated with Octreotide [O] . Tobias Skrebsky de Almeida, Rafaela Fenalti Salla, Alessandra Casagrande, 2020

机译：SAT-253患者的长期管理和成功怀孕用奥雷德雷德治疗的Macroadenoma治疗Macroadenoma
7. SAT-253 Long-Term Management and Successful Pregnancy of a Patient with a TSH Secreting Macroadenoma Treated with Octreotide [O] . Tobias Skrebsky de Almeida, Rafaela Fenalti Salla, Alessandra Casagrande, 2020

机译：SAT-253患者的长期管理和成功怀孕，用奥雷德雷德治疗的Macroadenoma治疗Macroadenoma
8. Gebruik van IRE-Medgenix Serum TSH IRMA voor de Bepaling van TSH in Hielprikbloedvan Pasgeborenen (Use of IRE-Medgenix Serum TSH IRMA for the Measurement of TSH in Bloodspots of Newborn Babies) [R] . Esmeijer, A., Eivers, L. H., Loeber, J. G. 1990

机译：Gebruik van IRE-medgenix血清TsH IRma voor de Bepaling van TsH in Hielprikbloedvan pasgeborenen（使用IRE-medgenix血清TsH IRma测量新生儿血瘀中的TsH）

Octreotide Changes Serum Thyrotropin (TSH) Glycoisomer Distribution as Assessedby Lectin Chromatography in a TSH Macroadenoma Patient

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