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Comparison of the Effects of High Dose Testosterone and 19-Nortestosterone to aReplacement Dose of Testosterone on Strength and Body Composition in Normal Men

机译：高剂量睾酮和19-去甲睾酮对睾酮替代剂量对正常男性力量和身体成分影响的比较

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摘要

Two androgen esters with very different anabolic/androgenic indices, testosteroneenanthate (TE) and 19-nortestosterone decanoate (ND) are frequently used in clinical practice and these two rank highest in popularity with athletes using parenteral preparations. TE and ND have similar halftimes to elimination of about 1 week, however, their metabolism to other biologically active compounds is different and this could be expected to modify their physiological activity. The 5 alpha-reduction of 19-nortestorone markedly reduces androgen receptor binding affinity which would imply a reduced action of tissues where intracellular 5-alpha reduction is important for the biological effect, such as in the accessory sex organs.

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Friedl, K. E.; Dettori, J. R.; Hannan, C. J.; Patience, T. H.; Plymate, S. R.;
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年度 1991
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总页数 6
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Testosterone; Biology; Clinical medicine; Dosage; Human body; Metabolism; Organs(Anatomy); Parenteral infusions; Physiology; Preparation; Reduction; Replacement; Sex; Tissues(Biology); Reprints;

机译：睾酮;生物学;临床医学;剂量;人体;代谢;器官（解剖学）;肠外输注;生理学;制备;减少;替代;性别;组织（生物学）;重印;

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1. Effects of oral testosterone undecanoate therapy on bone mineral density and body composition in 322 aging men with symptomatic testosterone deficiency: A 1-year, randomized, placebo-controlled, dose-ranging study [J] . BoulouxP.M.G., LegrosJ.-J., ElbersJ.M.H., The aging male: the official journal of the International Society for the Study of the Aging Male . 2013,第2期

机译：口服十一酸睾丸激素疗法对322名有症状睾丸激素缺乏的老年男性的骨矿物质密度和身体组成的影响：一项为期1年，随机，安慰剂对照，剂量范围研究
2. Dose-response effects of sex hormone concentrations on body composition and adipokines in medically castrated healthy men administered graded doses of testosterone gel [J] . Thirumalai Arthi, Rubinow Katya B., Cooper Lori A., Clinical Endocrinology . 2017,第1期

机译：性激素浓度对人体组成和脂肪因子在医学阉割的健康男性睾丸激素凝胶患者胶凝胶中的剂量 - 反应效应
3. The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. [J] . Bhasin S, Storer TW, Berman N, The New England journal of medicine . 1996,第1期

机译：超生理剂量的睾丸激素对正常男性肌肉大小和力量的影响。
4. Effects of dome size and dose loading on oral powderject~circleR delivery of testosterone to conscious beagle dogs [C] . D.J. Longridge, P.A. Sweeney, H. Millward, International symposium on controlled release of bioactive materials;Consumer and diversified products conference . 1998

机译：穹顶大小和剂量负荷对清醒比格犬口服睾丸粉末注射〜circR的影响
5. The effects of a 600 mg dose of soy phosphatidylserine on cortisol, growth hormone and testosterone response to moderate intensity exercise. [D] . Starks, Michael Anthony. 2008

机译：600 mg剂量的大豆磷脂酰丝氨酸对中度运动对皮质醇，生长激素和睾丸激素的影响。
6. Dose-response effects of sex hormone concentrations on body composition and adipokines in medically castrated healthy men administered graded doses of testosterone gel [O] . Arthi Thirumalai, Katya B. Rubinow, Lori A. Cooper, -1

机译：性激素浓度对服用分级剂量的睾丸激素凝胶的医学healthy割健康男性的身体成分和脂肪因子的剂量反应
7. The Effects of Testosterone Boosters on Testosterone, Strength, and Body Composition in Young Trained Males [O] . Gonzalez M., Harding B., Cattano N., 2016

机译：睾丸激素助推器对年轻受训男性睾丸激素，力量和身体成分的影响

Comparison of the Effects of High Dose Testosterone and 19-Nortestosterone to aReplacement Dose of Testosterone on Strength and Body Composition in Normal Men

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