首页> 美国政府科技报告 >Assessment of Dermal and Ocular Effects of Topical Skin Protectant FormulationsICD-1536 (Lot no. 11 Jan 91 BH) and ICD 1536 (Lot no. 03 Jan 91 AH) May 1991
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Assessment of Dermal and Ocular Effects of Topical Skin Protectant FormulationsICD-1536 (Lot no. 11 Jan 91 BH) and ICD 1536 (Lot no. 03 Jan 91 AH) May 1991

机译:评估局部皮肤保护剂制剂的皮肤和眼部效果ICD-1536(批号11月91日BH)和ICD 1536(批号03年1月91日aH)1991年5月

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摘要

Two separate lots of ICD-1536, a topical skin protectant formulation, wereevaluated for skin, eye, and photochemical irritation in rabbits. Lot No. 11 Jan 91 BH caused moderate primary skin irritation with erythema persisting through 7 days. It also produced minimal eye irritation but no photochemical irritation. It was recommended that the material be used with caution on human skin and that a prophetic patch test be performed on man to determine irritation potential to human skin. Lot No. 03 Jan 91 AH did not cause significant skin, eye or photochemical irritation in animals. It was recommended that it be approved for acute topical use in humans.

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