首页> 美国政府科技报告 >Expression in Escherichia coli K-12 of the 76, 000-Dalton Iron-Regulated Outer Membrane Protein of Shigella flexneri Confers Sensitivity to Cloacin DF13 in the Absence of Shigella O Antigen. (Reannouncement with New Availability Information).
【24h】

Expression in Escherichia coli K-12 of the 76, 000-Dalton Iron-Regulated Outer Membrane Protein of Shigella flexneri Confers Sensitivity to Cloacin DF13 in the Absence of Shigella O Antigen. (Reannouncement with New Availability Information).

机译:在福氏志贺菌的76,000道尔顿铁调节的外膜蛋白的大肠杆菌K-12中的表达赋予在没有志贺氏菌抗原的情况下对Cloacin DF13的敏感性。 (重新公布新的可用性信息)。

获取原文

摘要

One of the chromosomal segments associated with virulence in Shigella flexneri encodes the production of aerobactin and the synthesis of an iron-regulated 76-kilodalton outer membrane protein believed to be the ferric-aerobactin receptor. However, S. flexneri expressing this putative aerobactin receptor, which is slightly larger than that encoded by pColV, is insensitive to the killing action of cloacin DF13, a bacteriocin which binds to other aerobactin receptor proteins and kills the cells. In this paper we show that the conjugal transfer of DNA encoding the iron-regulated 76-kilodalton protein from S. flexneri to Escherichia coli K-12 conferred cloacin DF13 sensitivity on the recipients. However, E. coli K-12 which had also inherited genes specifying Shigella O-antigen biosynthesis remained cloacin insensitive.

著录项

相似文献

  • 外文文献
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号