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Methyl Prednisolone in the Treatment of Acute Spinal Cord Decompression Sickness.

机译：甲基强的松龙治疗急性脊髓减压病。

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Sixteen anesthetized dogs undertook a chamber dive that was designed to induce decompression sickness. Somatosensory evoked potentials (SEP) were used to diagnose and quantify the outcome of spinal cord involvement in the disease. Following diagnosis, 8 animals were treated with methyl prednisolone (MP), 20 mg . kg-1 ('megadose'), as an adjuvant to recompression on an abbreviated U.S. Navy Treatment Table 6. Eight control animals were recompressed in a similar manner, but received the MP diluent only as an adjuvant. Analysis of the SEP at the conclusion of treatment showed that there was no significant difference in outcome for th 2 groups of animals. However, if all the SEP recorded during the treatment period are compared, the MP-treated animals experienced a significantly worse outcome than the diluent-treated controls. The risks and benefit of using corticosteroids in the treatment of human spinal cord DCS are discussed. Keywords: Decompression; Sickness; Dysbarism; Therapy; Steroids; Central nervous system, Reprints. (KT)

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作者
Francis, T. J.; Dutka, A. J.;
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年度 1989
页码 1-11
总页数 11
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Decompression sickness; Spinal cord; Central nervous system; Chambers; Control; Corticosteroid agents; Diving; Dogs; Humans; Laboratory animals; Reprints; Therapy; Methyl Prednisolone; Pharmacology;

机译：减压病;脊髓;中枢神经系统;房间;对照;皮质类固醇剂;潜水;狗;人类;实验室动物;重印;治疗;甲泼尼龙;药理学;

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1. Risk factors and treatment outcome in scuba divers with spinal cord decompression sickness. [J] . Gempp E, Blatteau JE Journal of critical care . 2010,第2期

机译：潜水员脊髓减压病的危险因素和治疗结果。
2. MRI findings and clinical outcome in 45 divers with spinal cord decompression sickness. [J] . Gempp E, Blatteau JE, Stephant E, Aviation, space, and environmental medicine. . 2008,第12期

机译：45名潜水员脊髓减压病的MRI表现和临床结局。
3. Letter to the editor regarding: "Early versus delayed decompression for traumatic cervical spinal cord injury: Results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS)" [J] . Noauthornameavailable, VanMiddendorpJ.J. The spine journal: official journal of the North American Spine Society . 2012,第6期

机译：致编辑的信：“创伤性颈脊髓损伤的早期减压与延迟减压：急性脊髓损伤研究（STASCIS）的手术时机结果”
4. Treatment of Acute 'Deep Pain Negative' Thoracolumbar Spinal Cord Injury in Dogs by Extended Durotomy [C] . American College of Veterinary Internal Medicine Forum Conference . 2019

机译：延长杜疏孔治疗犬急性“深疼痛负”胸肺脊髓损伤
5. Review of the pathogenesis and treatment of acute spinal cord injury and investigation into the use of urine 3-HPMA as a novel biomarker of secondary injury after acute spinal cord injury in the dog. [D] . Sangster, Andrea. 2014

机译：回顾急性脊髓损伤的发病机理和治疗方法，并探讨使用尿液3-HPMA作为犬急性脊髓损伤后继发性损伤的新型生物标志物。
6. Spinal cord degeneration in a case of "recovered" spinal decompression sickness. [O] . A C Palmer, I M Calder, R I McCallum, 1973

机译：在“恢复的”脊髓减压病的情况下脊髓变性。
7. Spinal cord degeneration in a case of "recovered" spinal decompression sickness. [O] . Palmer, A.C., Calder, I.M., McCallum, R.I., 1981

机译：在“恢复的”脊髓减压病的情况下脊髓变性。

Methyl Prednisolone in the Treatment of Acute Spinal Cord Decompression Sickness.

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