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Gerbil, 'Meriones unguiculatus', a Model for Rift Valley Fever Viral Encephalitis

机译：Gerbil，'meriones unguiculatus'，裂谷热病病毒性脑炎模型

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The gerbil, Meriones unguiculatus, was investigated as a model for the encephalitic form of Rift Valley fever. Resistance to necrotizing encephalitis was age-dependent with 100% mortality at 3 weeks, decreasing to approximately 20% by 10 weeks of age in outbred gerbils inoculated subcutaneously. Fatal encephalitis in the 10-week-old adults was dose-dependent. Viral replication and histological lesions were followed serially throughout the course of the infection in young (4 week) and adult (10 week) gerbils. Viral replication was evident in the brain tissue of young gerbils from day 4 through 7, the last day the young gerbils survived. Virus was only detected in the brain tissue of a single adult gerbil (day 7), of 26 studied in the sequential survey. Reprints. (aw)

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作者
Anderson, G. W.; Slone, T. W.; Peters, C. J.;
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年度 1988
页码 p.1-10
总页数 10
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Encephalitis; Rift valley fever; Rift valley fever virus; Anatomical models; Adults; Brain; Histology; Laboratory animals; Lesions; Necrosis; Reprints; Resistance(Biology); Rodents; Sequences; Surveys; Tissues(Biology);

机译：脑炎;裂谷热;裂谷热病毒;解剖模型;成人;脑;组织学;实验动物;病变;坏死;重印;抗性（生物学）;啮齿动物;序列;调查;组织（生物学）;

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专利

1. The mongolian gerbil ( Meriones unguiculatus Meriones unguiculatus ) as a model for inflammation‐promoted prostate carcinogenesis [J] . Quintar Amado A., Gon?alves Bianca F., Taboga Sebasti?o R., Cell biology international. . 2017,第11期

机译：Mongolian Gerbil（MeriOnes Unguiculatus Merioges Unguiculatus）作为炎症促进的前列腺发生的模型
2. Chromatin Organization and Remodeling of Interstitial Telomeric Sites During Meiosis in the Mongolian Gerbil (Meriones unguiculatus) [J] . Alberto Viera, Jesús Page, Julio S. Rufas, Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2014,第4期

机译：蒙古沙鼠（Meriones unguiculatus）减数分裂期间的染色质组织和间质端粒位点的重塑
3. Epidemiological processes involved in the emergence of vector-borne diseases: West Nile fever, Rift Valley fever, Japanese encephalitis and Crimean-Congo haemorrhagic fever [J] . V. Chevalier S. de la Rocque, T. Baldet, L. Vial, Revue Scientifique et Technique . 2004,第2期

机译：媒介传播疾病的出现的流行病学过程：西尼罗河热，裂谷热，日本脑炎和克里米亚-刚果出血热
4. Coupling an Agent-Based Model with a Mathematical Model of Rift Valley Fever for Studying the Impact of Animal Migrations on the Rift Valley Fever Transmission [C] . Paul Python Ndekou Tandong, Papa Ibrahima Ndiaye, Alassane Bah, International Conference on Computational Science and Its Applications . 2020

机译：耦合基于代理的模型与裂谷发热的数学模型，用于研究动物迁移对裂谷发热传动的影响
5. Molecular modeling approach towards the discovery of inhibitors for Rift Valley Fever Virus nucleocapsid protein. [D] . Bonyi, Enock N. 2013

机译：发现裂谷热病毒核衣壳蛋白抑制剂的分子建模方法。
6. Chromatin Organization and Remodeling of Interstitial Telomeric Sites During Meiosis in the Mongolian Gerbil (Meriones unguiculatus) [O] . Roberto de la Fuente, Marcia Manterola, Alberto Viera, 2014

机译：蒙古沙鼠（Meriones unguiculatus）减数分裂期间的染色质组织和间质端粒位点的重塑
7. Preconditioning with L-Ala-Gln reduces the expression of inflammatory markers (TNF-α, NF-κB, IL-6 and HO-1) in an injury animal model of cerebrovascular ischemia in Meriones unguiculatus (gerbils) [O] . Leidelamar Rosário Alves de Oliveira, Andréa de Oliveira Albuquerque, Cícero Igor Simões Moura Silva, 2020

机译：用L-ALA-GLN的预处理减少了MeriOnes Unguiculatus（Gerbils）脑血管缺血的损伤动物模型中炎症标记（TNF-α，NF-κB，IL-6和HO-1）的表达
8. The Mongolian Gerbil (Meriones unguiculatus) as a Model for the Study of the Epilepsies: EEG Records of Seizures. [R] . Loskota, W. J., Lomax, P. 1975

机译：蒙古沙鼠（meriones unguiculatus）作为癫痫研究的模型：癫痫发作的脑电记录。

Gerbil, 'Meriones unguiculatus', a Model for Rift Valley Fever Viral Encephalitis

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