首页> 美国政府科技报告 >Indigenous Human Cutaneous Leishmaniasis Caused by 'Leishmania tropica' in Kenya. (Reannouncement with New Availability Information).
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Indigenous Human Cutaneous Leishmaniasis Caused by 'Leishmania tropica' in Kenya. (Reannouncement with New Availability Information).

机译:肯尼亚'利什曼原虫'引起的土着人类皮肤利什曼病。 (重新公布新的可用性信息)。

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摘要

Six Leishmania isolates from 3 indigenous Kenyans (2 isolates from one patient) and 2 Canadian visitors in Kenya were characterized by cellulose acetate electrophoresis. The isolates were compared among themselves and with reference strains of Leishmania donovani, L. aethiopica, L. major, L. tropica, and L. arabica using 9 enzymes: malate dehydrogenase (MDH), malic enzyme (ME), phosphogluconate dehydrogenase (6PGD), glucose-6-phosphate dehydrogenase (G6PD), aspartate aminotransferase (ASAT), adenylate kinase (AK), mannose phosphate isomerase (MPI), glucose phosphate isomerase (GPI), and phosphoglucomutase (PGM). Enzyme migration patterns of isolates from the 3 indigenous Kenyans were indistinguishable from those of 2 L. tropica reference strains. The isolates from the 2 Canadians yielded migration patterns of 7 enzymes that were indistinguishable from those of 2 L. tropica reference strains. However, migration patterns of 2 enzymes, PGM and ME, were different from all migration patterns of the 10 reference strains.

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