首页> 美国政府科技报告 >Preliminary Study of the Osteogenic Potential of a Biodegradable Alloplastic-Osteoinductive Alloimplant
【24h】

Preliminary Study of the Osteogenic Potential of a Biodegradable Alloplastic-Osteoinductive Alloimplant

机译:可生物降解的异体骨诱导异种移植物成骨潜能的初步研究

获取原文

摘要

A biodegradable copolymer of polylactide:polyglycolide (PLA:PGA) was combined with allogeneic decalcified freeze-dried bone (DFDB) and implanted into 15 mm diameter defects in the calvaria of 26 New Zealand White rabbits. Similar defects were created in the calvaria of another 26 rabbits. These animals served as controls and did not receive copolymer implants. Upon sacrifice, both the implants and the controls were evaluated clinically, radiographically, and histomorphometrically using a Zeiss Image Analysis System. Both controls and implants were evaluated in groups at 4, 8, 12, 16, 20, and 24 weeks. When compared with the control defects, the copolymer:DFDB implants displayed a significantly greater volume of trabecular bone. Three of the 15 mm diameter defects displayed evidence of complete osseous bridging at 8 weeks. No adverse host tissue responses were observed histologically in any of the implant specimens.

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号