• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国政府科技报告 >Canine Antithrombin-III: Some Biochemical and Biologic Properties.
【24h】

Canine Antithrombin-III: Some Biochemical and Biologic Properties.

机译：犬抗凝血酶-3：一些生化和生物学特性。

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Coagulopathies have been reported to occur after many forms of stress and trauma. These thrombohemorrhagic responses are likely consequent to disturbances of the delicate interplay of the hemostatic compartments (vasculature, platelets, and plasma proteins), resulting in the systemic activation of the clotting-fibrinolytic (and other) systems with eventual depletion of critical hemostatic components. This syndrome* of generalized intravascular proteolysis or disseminated intravascular coagulation (DIC), an intermediary mechanism of disease, is usually (but not always) associated with well-defined clinical entities. It can manifest as a wide clinical spectrum. For example, if the intravascular clotting process is dominant and secondary fibrino(geno)lysis minimal, DIC may be expressed primarily as diffuse thromboses, as in malignancy. Alternatively, if the secondary fibrinolysis which occurs with DIC is dominant, and the drive toward procoagulant activity minimal, the clinical manifestations will be hemorrhage, by far the more common expression of DIC (1-4). Patients often demonstrate combinations of these two clinical manifestations. Thus, DIC represents a wide spectrum of clinical findings with patients presenting anywhere in the continuum between diffuse thromboses and/or hemorrhage (1,4,5).

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号