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Cardiovascular and Hormonal Responses of Conscious Pigs during Physical Restraint

机译：有意识的猪在物理约束过程中的心血管和激素反应

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The authors investigated the effect of physical restraint on cardiovascular function and plasma hormone levels in 20 to 25 kg conscious Duroc pigs. Pigs were placed in a Pavlov sling or remained in a portable holding cage. Blood pressure and heart rate were monitored and blood samples taken at 0. 2.5, 5, 10, 30, 60, 120 and 240 min. Placement into the sling increased heart rate and mean arterial pressure. Both heart rate and blood pressure returned to basal values within 10 min. Hematocrit was increased. Heart rate, blood pressure and hematocrit were not changed in caged animals. Plasma norepinephrine increased returning to basal values within 10 min. Epinephrine showed a similar trend. Plasma renin activity increased after 5 min in the sling and remained increased from a basal level. ACTH and aldosterone rose over the four hr period. Pigs in cages showed no change in plasma hormones. Placement of a untrained pig into a sling raises heart rate, blood pressure and hematocrit and produces increases in plasma concentrations of epinephrine, ACTH, cortisol and aldosterone. Keywords: Laboratory animals stress (physiology); reprints.

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