• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国政府科技报告 >Vascular Casts Demonstrate Microcirculatory Insufficiency in Acute Frostbite
【24h】

Vascular Casts Demonstrate Microcirculatory Insufficiency in Acute Frostbite

机译：血管铸型显示急性冻伤的微循环不足

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The use of vascular microcorrosion casts has made it possible to demonstrate the degree of damage to the microcirculation in experimentally induced frostbite. This approach provides a direct method for demonstrating vascular patency. Four groups of animals were used in this investigation. The left hind limbs of anesthetized rats were cooled to -10 C in groups one and three and -20 C in groups two and four, as measured by needle thermocouples placed under the gastrocnemius muscles. Thermocouples were also placed in the left hind footpads of groups three and four. The sheathed limbs were cooled in an alcohol bath at approximately 1.1 C per minute. All cooled limbs were rewarmed to 37 C in a 40 C water bath. The right hind limbs served as uninjured controls. The footpad temperature recorded in groups three and four were used to characterize the footpad temperatures in groups one and two. Vascular microcorrosion casts were made from the left and right hind paws of groups one and two using Batson's modified methyl methacrylate. Scanning electron microscopic examination of the casts demonstrated dramatic differences between the vascular integrity of control paws and that of cooled paws. Exposure to the cold temperatures destroyed most of the microcirculation.

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号