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Tumorigenicity of Human Malignant Lymphoblasts: Comparative Study with Unmanipulated Nude Mice, Antilymphocyte Serum-Treated Nude Mice, and X-Irradiated Nude Mice

机译：人恶性淋巴母细胞的致瘤性：与未处理的裸鼠，抗淋巴细胞血清处理的裸鼠和X射线照射的裸鼠的比较研究

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The ability of unmanipulated, antilymphcyte serum (ALS)-treated, and x-irradiated nude BALB/c female mice (in their 13th backcross generation) to serve as hosts for 10 human lymphoblastoid cell lines as well as for peripheral blood lymphocytes from healthy human was compared. The 10 lymphoma lines included 7 previously characterized and reported in the literature. Significant differences with respect to both latency period for tumor appearance and success rate for tumor transplantation were detected among the 3 experimental groups. The unmanipulated mice were poor recipients for lymphoma hetrotransplants, and tumors were produced in two instances. In contrast, 6 tumor lines were successfully transplanted in mice inoculated with ALS, and all 10 lines were successfully transplanted into x-irradiated recipients.

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作者
Ohsugi, Y.; Gershwin, M. E.; Owens, R. B.; Nelson-Rees, W. A.;
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年度 1980
页码 p.1-6
总页数 6
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Lymphomas; Surgical transplantation; Females; Mice; Humans; Cells; Standardization; Histology; Cells(Biology); Neoplasms; Blood; Lymphocytes; Irradiation; X rays; Reprints;

机译：淋巴瘤;外科移植;雌性;小鼠;人类;细胞;标准化;组织学;细胞（生物学）;肿瘤;血液;淋巴细胞;辐射; X射线;重印;

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专利

1. The human Y chromosome suppresses the tumorigenicity of PC-3, a human prostate cancer cell line, in athymic nude mice. [J] . Vijayakumar S, Garcia D, Hensel CH, Genes, Chromosomes and Cancer . 2005,第4期

机译：人Y染色体抑制了无胸腺裸鼠中PC-3（人前列腺癌细胞系）的致癌性。
2. Engraftment of human glioblastoma for tumorigenicity evaluation through intracerebroventricular injection in BALB/c nude mice [J] . Noh Jung-Ho, Lee Byoung-Seok, Kim Jong-Wan, Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research . 2017,第S1期

机译：通过颅内腔内注射在Balb / C裸鼠中植入人胶质母细胞瘤的植入
3. Scaffold-Free Coculture Spheroids of Human Colonic Adenocarcinoma Cells and Normal Colonic Fibroblasts Promote Tumorigenicity in Nude Mice [J] . Jong-il Park, Jisu Lee, Ju-Lee Kwon, Translational Oncology . 2016,第1期

机译：人结肠腺癌细胞和正常结肠成纤维细胞的无支架共培养球体可促进裸鼠的致瘤性。
4. Ultrastructural study on regional administration of phosphorus-32 glass microspheres in treating implanted human hepatic carcinoma in nude mice [C] . Dongsheng Zhang, Lu Liu, Jishan Zhu, Proceedings of International Kunming Symposium on Microscopy July 2-5, 2000 Kunming, Yunnan Province, China . 2000

机译：磷32玻璃微球局部给药治疗裸鼠人肝癌的超微结构研究
5. An investigation of the effects of vitamin E succinate (VES) on human prostate LNCaP tumor growth and gene expression in BALB/c nude mice fed high-fat diets. [D] . Aredo, Bogale. 2011

机译：研究维生素E琥珀酸酯（VES）对高脂饮食喂养的BALB / c裸鼠中人前列腺LNCaP肿瘤生长和基因表达的影响。
6. Tumorigenicity of simian virus 40-transformed human cells and mouse--human hybrids in nude mice. [O] . H Koprowski, C M Croce 1977

机译：猿猴病毒40转化的人细胞和小鼠-人杂种在裸鼠中的致瘤性。
7. Study on heterotransplantation of human malignant urogenital tumors in nude mice: establishment of the tumor line in nude mice from human primary ureteral tumor and its characteristics [O] . 深津英捷, 山田博彦, 野々村仁志, 1987

机译：人恶性泌尿生殖系统肿瘤裸鼠异种移植的研究：人原发性输尿管肿瘤裸鼠肿瘤线的建立及其特征
8. Wound Healing Using Nude Immuno-Deficient Mice and Human Skin Transplanted ontoNude Mice: A Comparative Study (Getransplanteerde Mensenhuid op Naakte Muizen als Model voor Wondheling) [R] . Elliott, G. R., Fasbender, M. J., Hammer, A. H., 1990

机译：使用裸体免疫缺陷小鼠和人类皮肤移植到裸鼠身上的伤口愈合：比较研究（Getransplanteerde mensenhuid op Naakte muizen als model voor Wondheling）

Tumorigenicity of Human Malignant Lymphoblasts: Comparative Study with Unmanipulated Nude Mice, Antilymphocyte Serum-Treated Nude Mice, and X-Irradiated Nude Mice

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