首页> 美国政府科技报告 >Fasciotomy Reduces Compartment Pressures and Improves Recovery in a Porcine Model of Extremity Vascular Injury and Ischemia-Reperfusion.
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Fasciotomy Reduces Compartment Pressures and Improves Recovery in a Porcine Model of Extremity Vascular Injury and Ischemia-Reperfusion.

机译:Fasciotomy减少房间压力,改善猪肢体血管损伤和缺血再灌注模型的恢复。

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摘要

The objective of this study is to establish a model of extremity compartment syndrome following vascular injury/hemorrhage and ischemia/reprovision. An additional objective is to determine the effect of fasciotomy on measures of neuromuscular recovery. Methods: Yorkshire swine/e (75+/-5kg) underwent 35% blood volume hemorrhage, followed by 1, 3 and 6 hours of ischemia (n-17; 1HR, 3HR, 6HR) via iliac artery occlusion followed by repair and reperfusion. A second cohort (n=18) underwent fasciotomy of the anterior compartment of the hind limb following vascular repair (lHRwF/3HRwF, 6HR-F). Compartment pressures and measures of electromyographic (EMG) recovery were performed throughout a 14 day survival period and tissue histology examined at the completion of the study.

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