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Effect of Acid Load and Acetazolamide on Acid Loss in Distal Duodenal Pouches.

机译：酸负荷和乙酰唑胺对十二指肠远端小肠酸丢失的影响。

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Duodenal pouches even without Brunner's glands are able to dispose of large amounts of acid, presumably by a combination of H+ 'back diffusion' and bicarbonate secretion. This ability is a function of H+ concentration and hence H+ load. In order to study this mechanism, duodenal pouches 10 cm long were created distal to the duct of wirsung in 5 adult mongrel dogs. The duodenal acid disposal mechanism is dependent on acid load as determined either by H+ concentration or rate of acid delivery. This mechanism becomes less efficient as the load is increased. Some of the duodenal acid loss may be due to bicarbonate secretion since diamox inhibits carbonic anhydrase; diamox also inhibits chloride absorption which might explain less bicarbonate secretion because of chloride bicarbonate exchange.

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作者
Gurll, N. J.; Harmon, J. W.; Callahan, W.;
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年度 1976
页码 1-5
总页数 5
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Acids; Duodenum; Acetazolamide; Bicarbonates; Diffusion; pH factor; Perfusion; Gastrointestinal system; Reprints;

机译：酸;十二指肠;乙酰唑胺;碳酸氢盐;扩散; pH值因子;灌注;胃肠系统;重印;

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专利

1. Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia. [J] . Faller G, Dimmler A, Rau T, Journal of Pathology: Journal of the Pathological Society of Great Britain and Ireland . 2004,第4期

机译：十二指肠胃化生中酸诱导的Cdx2表达丧失的证据。
2. Duodenal epithelial cells provide a stimulus package for the recovery from an acid load. [J] . Okamoto CT The Journal of Physiology . 2009,第14期

机译：十二指肠上皮细胞为从酸性负荷中恢复提供刺激包。
3. Tranexamic Acid Reduces Postoperative Blood Loss in Distal Femoral Osteotomy [J] . The journal of knee surgery . 2020,第5期

机译：Tranexamic酸可降低远端股骨骨质术中的术后失血
4. REDUCTION OF DIETARY ACID LOAD AS A POTENTIAL COUNTERMEASURE FOR BONE LOSS ASSOCIATED WITH SPACEFLIGHT [C] . S. R. Zwart, S. M. Watts, C. F. Sams, International Astronautical Congress(IAC2006); 20061002-06; Valencia(ES) . 2006

机译：降低饮食中的酸负荷作为与航天飞行有关的骨质流失的可能对策
5. Calcium absorption in the human distal colon: Effect of short-chain fatty acids from fiber fermentation. [D] . Trinidad, Trinidad Palad. 1997

机译：人的远端结肠中钙的吸收：来自纤维发酵的短链脂肪酸的影响。
6. Validation of the difference in urine and blood carbon dioxide tension during bicarbonate loading as an index of distal nephron acidification in experimental models of distal renal tubular acidosis. [O] . T D DuBose Jr, C R Caflisch 1985

机译：在远端肾小管性酸中毒实验模型中验证碳酸氢盐负荷期间尿液和血液中二氧化碳张力的差异作为远端肾单位酸化的指标。
7. Effect of fat on meal-stimulated duodenal acid load, duodenal pepsin load, and serum gastrin in duodenal ulcer and normal subjects [O] . Robert A. Gross, Jon I. Isenberg, Daniel Hogan, 1978

机译：脂肪对十二指肠溃疡和正常主题中膳食刺激十二指肠酸载荷，十二指肠胃蛋白含量和血清胃泌素的影响

Effect of Acid Load and Acetazolamide on Acid Loss in Distal Duodenal Pouches.

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