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首页> 美国政府科技报告 >Quantitative Relationship of Ureaplasma Urealyticum to the Clinical Course of Nongonococcal Urethritis in the Human Male.
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Quantitative Relationship of Ureaplasma Urealyticum to the Clinical Course of Nongonococcal Urethritis in the Human Male.

机译：解脲支原体与人类男性非淋菌性尿道炎临床病程的定量关系。

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摘要

The pathogenic role of Ureaplasma urealyticum (T Mycoplasma)in nongonococcal urethritis (NGU) was examined by a quantitative cultural method. Selected male patients with primary or recurrent U. urealyticum-associated NGU were treated with reduced regimens of tetracyclines in an attempt to induce a 50% or greater relapse rate. Assessment of significant of U. urealyticum association to the clinical course of NGU was measured by quantitative urine cultures employing a urease color test medium. Of 23 NGU patients followed, 12 were cured, two were treatment failures and nine relapsed following an eclipse period, during which all symptoms were normal and cultures were negative. Relapse was heralded by a return of positive Ureaplasma agar cultures and a rising urine titer, which was accompanied clinically by simultaneous reappearance of dysuria. This was followed, in turn, by return of urethral discharge an average of 6.1 days later, and reestablishment of the disease. U. urealyticum urine titers attained or exceeded pretreatment levels in all nine NGU patients who relapsed. The evidence presented, showing a close, quantitative relationship of U. urealyticum to the clinical course of NGU in relapse, supports a pathogenic role of this organism in the etiology of NGU.

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