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SOME EFFECTS OF THE AIR POLLUTANT, PEROXYACETYL NITRATE, UPON DEOXYRIBONUCLEIC ACID AND UPON NUCLEIC ACID BASES,

机译：空气污染物，过氧乙酸硝酸盐，脱氧核糖核酸和核酸碱的一些影响，

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Some reactions between the air pollutant peroxyacetyl nitrate (PAN) and isolated bacterial deoxyribonucleic acid (DNA) are presented. PAN CAUSES A REDUCTION IN GENETIC TRANSFORMING ACTIVITY4 MELTING TEMPERATURE AND VISCOSITY OF THE DNA. PAN also reduces the infectivity of bacteriophage. It is shown that the intensity and type of reaction is pH dependent,and that the reaction depends upon the presence of a rapidly dissipated transient molecule produced from PAN as it enters solution. Furthermore, peroxyacetyl nitrate modifies some nucleic acid bases,when freshly gassed into aqueous solutions of the base. The susceptibility sequence to PAN attack is thymine,guanine,uracil,cytosine,adenine. No reaction was detected above pH5,and the reaction rate increases as the pH is lowered. One of the reaction products is CO2,which is excised from the 2-carbon of thymine. This reaction predominates at pH4whereas at pH2at least 5reaction products are produced,including CO2. (Author)

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作者
belser,william l. peak, m. j.;
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年度 1970
页码 1-14
总页数 14
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
air pollution; mutations; desoxyribonucleic acids; chemical reactions; nucleic acid components; chemical reactionsnitrates; peroxides; in vitro analysis; purines; pyrimidines;

机译：空气污染;突变;脱氧核糖核酸;化学反应;核酸成分;化学反应硝酸盐;过氧化物;体外分析;嘌呤;嘧啶;

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专利

1. A physiological and morphological study on the injury caused by exposure to the air pollutant, peroxyacetyl nitrate (PAN), based on the quantitative assessment of the injury [J] . Oka E, Tagami Y, Oohashi T, Journal of Plant Research . 2004,第1期

机译：基于对伤害的定量评估，对暴露于空气污染物过氧化乙酰硝酸盐（PAN）造成的伤害进行生理和形态学研究
2. Mutagenicity in lung of big Blue((R)) mice and induction of tandem-base substitutions in Salmonella by the air pollutant peroxyacetyl nitrate (PAN): predicted formation of intrastrand cross-links. [J] . DeMarini DM, Shelton ML, Kohan MJ, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2000,第1a2期

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3. Eletrostatic Repulsion And Steric Hindrance Effects Of Surface Probe Density On Deoxyribonucleic Acid (dna)/peptide Nucleic Acid (pna) Hybridization [J] . Fei Xu, August M, Pellino, Thin Solid Films . 2008,第23期

机译：表面探针密度对脱氧核糖核酸（dna）/肽核酸（pna）杂交的静电排斥和立体阻滞作用
4. Nucleic Acids Chemistry beyond the Watson-Crick Double Helix(61):Effect of Neighboring Base Pairs of Cytosine Bulge onBerberine Induced RNA Stabilization [C] . Sagar Satpathi, Tamaki Endoh, Naoki Sugimoto 日本化学会春季年会 . 2020

机译：核酸化学超出Watson-Crick双螺旋（61）：邻近胞嘧啶凸起的肌肉肿瘤诱导RNA稳定的效果
5. Occurrence and Function of Hoogsteen Base Pairs in Nucleic Acids. [D] . Zhou, Huiqing. 2016

机译：Hoogsteen碱基对在核酸中的发生和功能。
6. Effects of Ozone and Peroxyacetyl Nitrate on Polar Lipids and Fatty Acids in Leaves of Morning Glory and Kidney Bean [O] . Isamu Nouchi, Susumu Toyama 1988

机译：臭氧和硝酸过氧乙酰硝酸盐对牵牛花和菜豆叶片极性脂质和脂肪酸的影响
7. Effects of Ozone and Peroxyacetyl Nitrate on Polar Lipids and Fatty Acids in Leaves of Morning Glory and Kidney Bean [O] . Nouchi, Isamu, Toyama, Susumu 1988

机译：臭氧和过氧乙酰硝酸盐对牵牛花和菜豆叶片极性脂质和脂肪酸的影响
8. Acidic Deposition: State of Science and Technology. Report 22. Direct Health Effects of Air Pollutants Associated with Acidic Precursor Emissions [R] . Graham, J. A., Grant, L. D., Folinsbee, L. J., 1990

机译：酸性沉积：科学技术状况。报告22.与酸性前体排放有关的大气污染物的直接健康影响

SOME EFFECTS OF THE AIR POLLUTANT, PEROXYACETYL NITRATE, UPON DEOXYRIBONUCLEIC ACID AND UPON NUCLEIC ACID BASES,

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