• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国政府科技报告 >Alternatives to Autograft Evaluated in a Rabbit Segmental Bone Defect.
【24h】

Alternatives to Autograft Evaluated in a Rabbit Segmental Bone Defect.

机译：在兔节段性骨缺损中评估自体移植物的替代方案。

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose This study was designed to identify strategies for treating bone defects that can be completed on the day of surgery. Methods Forty New Zealand white rabbits with unilateral rabbit radius segmental defects (15 mm) were treated with commercially available scaffolds containing either demineralised bone matrix (DBM) or a collagen/beta-tricalcium phosphate composite (Col: -TCP); each scaffold was combined with either bone marrow aspirate (BMA) or concentrated BMA (cBMA). Bone regeneration was assessed through radiographic and histological analyses. Results The concentration of nucleated cells, colony-forming unit-fibroblasts and platelets were increased and haematocrit concentration decreased in cBMA as compared to BMA (p<0.05). Radiographic analyses of bone formation and defect bridging demonstrated significantly greater bone regeneration in the defects treated with DBM grafts as compared to Col: -TCP grafts. The healing of bones treated with Col: - TCP was improved when augmented with cBMA. Conclusions Scaffolds containing either DBM or Col: -TCP with BMA or cBMA are effective same-day strategies available to clinicians for the treatment of bone defects; the latter scaffold may be more effective if combined with cBMA.

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号