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Racial Differences in Lifestyle Modification in Men with Newly- Diagnosed Prostate Cancer

机译：新诊断前列腺癌患者生活方式改变的种族差异

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The purpose of this investigation is to determine whether men diagnosed with prostate cancer make changes in dietary intake, physical activity, and use of dietary supplements, and the extent to which these changes differ by race (African American versus Caucasian American). The study also seeks to determine whether alterations in dietary intake and dietary supplement use among prostate cancer patients are associated with changes in oxidative DNA damage in lymphocytes and serum prostate specific antigen (PSA) levels. The project builds upon a Department of Defense-sponsored CaP Consortium titled 'Racial Differences in Prostate Cancer: Influences of Health Care and Host and Tumor Biology.' For this longitudinal study, a subset of Consortium participants in North Carolina (125 African Americans and 125 Caucasian Americans) will be recruited and followed for a period of 2 years. Data will be collected at baseline by the Consortium and at 12 months and 24 months postdiagnosis using similar methodology. Institutional Review Board approval has been obtained from both the funding agency (i.e., the DoD) and from the University of North Carolina. Study staff have been hired and trained. Participant enrollment and data collection will begin in September 2006. An abstract describing the study design was presented at the 2006 Experimental Biology Annual Conference.

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