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首页> 美国政府科技报告 >Changes in the Intracranial Rheoencephalogram at Lower Limit of Cerebral Blood Flow Autoregulation
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Changes in the Intracranial Rheoencephalogram at Lower Limit of Cerebral Blood Flow Autoregulation

机译：脑血流自动调节下限颅内脑血流图的变化

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Cerebral blood flow (CBF) reactivity monitoring is an appropriate primary parameter to evaluate cerebral resuscitation due to a systemic or regional cerebral injury leading to possible irreversible brain injury. Use of the electrical impedance method to estimate CBF is rare, as the method's anatomical background is not well understood. Use of intracranial rheoencepholography (iREG) during hemorrhage, and comparison of iREG to other CBF measurements, have not been previously reported. Our hypothesis was that iREG would reflect early cerebrovascular alteration (CBF autoregulation). Studies comparing iREG, laser Doppler flowmetry, and ultrasound were undertaken on anesthetized rats to define CBF changes during hemorrhage. Blood was removed at a rate required to achieve a mean arterial blood pressure (MABP) of 40 mmHg over 15 min. Estimation of CBF was taken with intracranial, bipolar REG (REG I; n = 14), laser Doppler flowmetry (LDF; n = 3), and carotid flow by ultrasound (n = 11). Data were processed off-line.

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